Kitamura Kei-ichiro, Takeuchi Ryuya, Ogai Kazuhiro, Xin Zhu, Chen Wenxi, Nemoto Tetsu
Department of Clinical Laboratory Science, Graduate School of Medical Science, Kanazawa University, Kanazawa, Ishikawa 920-0942, Japan.
Department of Clinical Laboratory Science, Graduate School of Medical Science, Kanazawa University, Kanazawa, Ishikawa 920-0942, Japan.
Med Eng Phys. 2014 Jul;36(7):927-32. doi: 10.1016/j.medengphy.2014.02.024. Epub 2014 Mar 25.
The aim of this study is to develop a painless system of measuring the brachial-ankle arterial pulse wave velocity (baPWV) without compression cuffs. The PWV reflects the compliance of the artery and is measured for the early diagnosis of arteriosclerotic vascular diseases. However, the conventional baPWV system, which measures four cuff pressures simultaneously, easily causes circulation block and tightening pain at the extremities. In addition, approximately 15 min are required to stabilise the blood pressure for re-examination. Therefore, we developed a novel baPWV measurement system using dual piezoelectric sensor elements. The principle of this high-sensitivity pressure pulse detection system is based on adding the two in-phase outputs from the coaxially arranged dual piezoelectric sensor. As our system facilitates the measurement of the baPWV by detecting the pulsation of an artery using sensors fixed on the skin where the pulse is palpable, it does not cause pain and reduces examination time. The coefficients of correlation between the baPWV values obtained from the conventional and present methods were 0.93 (right side) and 0.90 (left side). The results suggest that our system can be used to measure the baPWV without pressure cuffs as accurately as the conventional method.
本研究的目的是开发一种无需加压袖带的无痛测量肱踝动脉脉搏波速度(baPWV)的系统。脉搏波速度反映了动脉的顺应性,用于动脉硬化性血管疾病的早期诊断。然而,传统的baPWV系统同时测量四个袖带压力,容易导致循环阻滞和四肢紧绷疼痛。此外,重新检查时需要大约15分钟来稳定血压。因此,我们开发了一种使用双压电传感器元件的新型baPWV测量系统。这种高灵敏度压力脉冲检测系统的原理是基于将同轴排列的双压电传感器的两个同相输出相加。由于我们的系统通过使用固定在可触及脉搏的皮肤上的传感器检测动脉搏动来促进baPWV的测量,所以不会引起疼痛并减少了检查时间。从传统方法和本方法获得的baPWV值之间的相关系数分别为0.93(右侧)和0.90(左侧)。结果表明,我们的系统可用于在无压力袖带的情况下测量baPWV,其准确性与传统方法相当。