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皮肤粘弹性的局域表面波光学跟踪。

Optical tracking of local surface wave for skin viscoelasticity.

机构信息

The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Department of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 71004, PR China.

The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Department of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 71004, PR China.

出版信息

Med Eng Phys. 2014 Jun;36(6):708-14. doi: 10.1016/j.medengphy.2014.02.022. Epub 2014 Mar 24.

DOI:10.1016/j.medengphy.2014.02.022
PMID:24674744
Abstract

Rapid and effective determination of biomechanical properties is important in examining and diagnosing skin thermal injury. Among the methods used, viscoelasticity quantification is one of the most effective methods in determining such properties. This study aims to rapidly determine skin viscoelasticity by optically tracking the local surface wave. New elastic and viscous coefficients were proposed to indicate skin viscoelasticity based on a single impulse response of the skin. Experiments were performed using fresh porcine skin samples. Surface wave was generated in a single impulse using a vibrator with a ball-tipped device and was detected using a laser Doppler vibrometer. The motions along the depth direction were monitored using an ultrasound system. The ultrasound monitoring results indicated the multi-layered viscoelasticity of the epidermis and dermis. The viscoelastic coefficients from four healthy samples show a potential viscoelasticity variation of porcine skin. In one sample, the two coefficients were evidently higher than those in a healthy area if the skin was slightly burned. These results indicate that the proposed method is sensitive, effective, and quick in determining skin viscoelasticity.

摘要

快速有效地确定生物力学特性对于检查和诊断皮肤热损伤非常重要。在使用的方法中,粘弹性量化是确定这些特性的最有效方法之一。本研究旨在通过光学跟踪局部表面波来快速确定皮肤的粘弹性。根据皮肤的单次脉冲响应,提出了新的弹性和粘性系数来表示皮肤的粘弹性。使用新鲜的猪皮样本进行了实验。使用带有球形尖端装置的振动器在单个脉冲中产生表面波,并使用激光多普勒测振仪进行检测。使用超声系统监测沿深度方向的运动。超声监测结果表明表皮和真皮具有多层粘弹性。四个健康样本的粘弹性系数显示了猪皮的潜在粘弹性变化。在一个样本中,如果皮肤稍有烧伤,两个系数明显高于健康区域的系数。这些结果表明,所提出的方法在确定皮肤粘弹性方面是敏感、有效和快速的。

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Dynamic viscoelastic models of human skin using optical elastography.利用光学弹性成像技术建立的人体皮肤动态粘弹性模型。
Phys Med Biol. 2015 Sep 7;60(17):6975-90. doi: 10.1088/0031-9155/60/17/6975. Epub 2015 Aug 25.