Carpeggiani Clara
Recenti Prog Med. 2014 Mar;105(3):93-9. doi: 10.1701/1434.15868.
Medical imaging is one of the major cause of rising health care costs. Diagnostic imaging has increased more rapidly than any other component of medical care. About 5 billion imaging tests are performed worldwide each year. According to recent estimates, at least one-third of all examinations are partially or totally inappropriate. Two out of 3 imaging tests employ ionizing radiations with radiology or nuclear medicine. The medical use of radiation is the largest man-made source of radiation exposure. Medical X-rays and γ-rays are a proven human carcinogen. The attributable long-term extra-risk of cancer due to diagnostic testing is around 10% in industrialized countries. Cardiologists prescribe and/or directly perform >50% of all imaging examinations, accounting for about two-thirds of the total effective dose given to patients. The dose of common cardiological examinations may be significant: 500 chest X-rays= a stress scintigraphy with sestamibi, 750 chest X-rays= a Multislice Computed Tomography, 1,000 chest X-rays= a coronary angiography and stenting. Unfortunately, few doctors are aware of the level of radiation their patients are exposed to during radiological tests and more intensive use of ionizing testing was not associated with greater awareness. Also as a consequence of unawareness, the rate of inappropriate examinations is unacceptably high in cardiology, even for procedures with high radiation load. Higher exposure doses correspond to higher long-term risks; there are no safe doses, and all doses add up in determining the cumulative risks over a lifetime. Doctors should make every effort so that «each patient should get the right imaging exam, at the right time, with the right radiation dose», as suggested by US Food and Drug Administration in the 2010 initiative to reduce unnecessary radiation exposure from medical imaging. This is best obtained through a systematic implementation of the "3 A's strategy" proposed by the International Atomic Energy Agency in 2010: audit (of true delivered dose); appropriateness (since at least one-third of examinations are inappropriate); awareness (since the knowledge of doses and risks is largely). The regular application of "3 A's strategy" is usually not facilitated by a health system that pays for volumes, not for appropriateness.
医学成像检查是医疗保健成本不断攀升的主要原因之一。诊断成像检查的增长速度比医疗保健的任何其他组成部分都要快。全球每年大约进行50亿次成像检查。根据最近的估计,所有检查中至少三分之一部分或完全不适当。三分之二的成像检查采用放射学或核医学的电离辐射。医疗辐射的使用是人为辐射暴露的最大来源。医用X射线和γ射线是已被证实的人类致癌物。在工业化国家,因诊断性检查导致的癌症长期额外风险约为10%。心脏病专家开出和/或直接进行的成像检查占所有成像检查的50%以上,约占给予患者的总有效剂量的三分之二。常见心脏病检查的剂量可能很大:500次胸部X光检查 = 一次使用司他米比的负荷心肌灌注显像;750次胸部X光检查 = 一次多层螺旋CT检查;1000次胸部X光检查 = 一次冠状动脉造影和支架植入术。不幸的是,很少有医生了解患者在放射学检查期间所接受的辐射水平,而且电离检查的更频繁使用与更高的认识水平并无关联。同样由于缺乏认识,心脏病学中不适当检查的比例高得令人无法接受,即使是对于辐射负荷高的检查程序也是如此。更高的暴露剂量对应更高的长期风险;不存在安全剂量,并且所有剂量在确定一生的累积风险时都会累加。医生应尽一切努力,以便如美国食品药品监督管理局在2010年减少医学成像不必要辐射暴露的倡议中所建议的那样,“每位患者都应在正确的时间、接受正确的成像检查、接受正确的辐射剂量”。这最好通过系统实施国际原子能机构在2010年提出的“3A策略”来实现:审核(实际给予的剂量);适宜性(因为至少三分之一的检查是不适当的);认识(因为对剂量和风险很大程度上缺乏了解)。按数量付费而非按适宜性付费的卫生系统通常不利于“3A策略”的定期应用。