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乳腺癌骨转移:一项在选定放疗科室开展的流行病学研究。

Breast cancer bone metastases: an epidemiologic study in selected radiation departments.

作者信息

Runco Raffaele, Laganà Simona, Marino Giacomo, Di Grazia Alfio, Marino Lorenza, Umina Vincenza, Girlando Andrea, Ricottone Nicola, D'Agostino Antonino, Marletta Francesco, Tamburo Maria, Corsaro Giuseppe, Rallo Francesco, Santacaterina Anna, Acquaviva Grazia, Crispi Manuela, Palazzolo Carmela, Platania Angelo, Spatola Corrado, Privitera Giuseppe, Frosina Pasquale, Garufi Giuseppe, Bonanno Salvatore, Rosso Alberto, Barone Vincenzo, Corallo Anna, Sansotta Giuseppe, Delia Pietro, Donato Valentino, Lopes Salvatore, Pisana Michele, Borzì Francesca, Iatì Giuseppe, Potami Antonio, Messina Giovanna, Parisi Silvana, Frosina Luciano, Marletta Dario, De Renzis Costantino, Pontoriero Antonio, Pergolizzi Stefano

出版信息

Tumori. 2014 Jan-Feb;100(1):38-41. doi: 10.1700/1430.15813.

DOI:10.1700/1430.15813
PMID:24675489
Abstract

AIMS

To quantify radiation treatments for bone metastases from breast cancer in three Sicilian provinces (Messina, Catania, Ragusa) with respect to the general population and the incidence and prevalence of breast cancer in this macro-area in a 8-year period.

METHODS

All bone metastasis patients treated using radiotherapy in 8 radiation departments operating in the provinces of Messina, Catania and Ragusa were collected. Among these, metastases from breast carcinoma were analyzed according to year of irradiation. An analysis of breast cancer incidence and prevalence with respect to inhabitants in this macro-area was conducted using literature and census data.

RESULTS

From January 2004 to December 2011, irradiation was delivered in 4419 bone metastasis patients. Among these, 1617 had a primary breast cancer with a median treatment per year of 206.5 (range, 164-251); 211 patients were treated in 2004 and 206 in 2011. In 2004, there were 1,048,957 female residents in the three provinces and 1,065,422 in 2011. The reported breast cancer incidence and prevalence in Sicily was respectively 100.79/100,000 and 908.54/100,000 in 2004 and 108.41/100,000 and 1091.29/100,000 in 2010.

CONCLUSIONS

There has been an increase in both incidence and prevalence of breast cancer in Sicily. Nevertheless, it seems that there was no increment in skeletal-related events requiring irradiation in such patients in eastern Sicily radiation departments.

摘要

目的

量化西西里岛三个省份(墨西拿、卡塔尼亚、拉古萨)针对乳腺癌骨转移的放射治疗情况,并与一般人群以及该大区8年期间乳腺癌的发病率和患病率进行对比。

方法

收集了在墨西拿、卡塔尼亚和拉古萨三省8个放射科接受放射治疗的所有骨转移患者。其中,根据照射年份对乳腺癌转移患者进行了分析。利用文献和人口普查数据,对该大区居民的乳腺癌发病率和患病率进行了分析。

结果

2004年1月至2011年12月,4419例骨转移患者接受了照射。其中,1617例患有原发性乳腺癌,每年的中位治疗例数为206.5例(范围为164 - 251例);2004年有211例患者接受治疗,2011年为206例。2004年,三省女性居民有1,048,957人,2011年为1,065,422人。西西里岛报告的乳腺癌发病率和患病率在2004年分别为100.79/10万和908.54/10万,2010年分别为108.41/10万和1091.29/10万。

结论

西西里岛乳腺癌的发病率和患病率均有所上升。然而,西西里岛东部放射科此类患者中需要照射的骨相关事件似乎没有增加。

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Breast cancer bone metastases: an epidemiologic study in selected radiation departments.乳腺癌骨转移:一项在选定放疗科室开展的流行病学研究。
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