Hirasé Y, Valauri F A, Buncke H J
Microsurgical Replantation Transplantation Department.
Br J Plast Surg. 1989 Mar;42(2):216-22. doi: 10.1016/0007-1226(89)90207-5.
In a rat model, based on the concept of neovascularisation, an interposition vein-grafted arterial-venous fistula pedicle was used to create neovascularised skin, muscle, and bone free flaps. The important feature of these flaps is that neovascularisation of the selected flap tissues was achieved with a vein graft, unlike earlier studies using local arteries and veins as pedicles. Within a few weeks sufficient neovascularisation developed to support free transfer of the flaps based on the implanted vein graft pedicle. After successful transfer these flaps were harvested for histological examination. The implications of the clinical application of this technique are discussed.
在大鼠模型中，基于新血管形成的概念，采用静脉移植动脉-静脉瘘蒂来构建具有新生血管的皮肤、肌肉和骨游离皮瓣。这些皮瓣的重要特征是，与早期使用局部动静脉作为蒂的研究不同，所选皮瓣组织的新生血管形成是通过静脉移植实现的。在几周内，基于植入的静脉移植蒂形成了足够的新生血管，以支持皮瓣的游离移植。成功移植后，采集这些皮瓣进行组织学检查。讨论了该技术临床应用的意义。
