López-Martínez A E, Ramírez-Maestre C, Esteve R
Faculty of Psychology, Department of Personality, Assessment and Psychological Treatment, University of Málaga, Spain.
Eur J Pain. 2014 Sep;18(8):1129-38. doi: 10.1002/j.1532-2149.2014.00459.x. Epub 2014 Feb 19.
The tendency to respond with fear and avoidance can be seen as a shared vulnerability contributing to the development of post-traumatic stress disorder (PTSD) and chronic pain. Although several studies have examined which specific symptoms of PTSD (re-experiencing, avoidance, emotional numbing and hyperarousal) are associated with chronic pain, none has considered this association within the framework of fear-avoidance models.
Seven hundred fourteen patients with chronic musculoskeletal pain were assessed. Of these, 149 patients were selected for the study based upon the following inclusion criteria: exposure to a traumatic event before the onset of pain (with scores equal to or higher than 8 points on the fear and hopelessness scales of the Stressful Life Event Screening Questionnaire Revised) and scores equal to or higher than 30 on the Davidson Trauma Scale.
Structural equation modelling was used to test the association between PTSD symptoms and pain outcomes (pain intensity and disability) using the mediating variables considered in the fear-avoidance models. The results show that emotional numbing and hyperarousal symptoms, but neither re-experiencing nor avoidance, affected pain outcome via anxiety sensitivity (AS), catastrophizing and fear of pain. PTSD symptoms increased the levels of AS, which predisposes to catastrophizing and, in turn, had an effect on the tendency of pain patients to respond with more fear and avoidance.
This study provides empirical support for the potential role of PTSD symptoms in fear-avoidance models of chronic pain and suggests that AS is a relevant variable in the relationship between both disorders.
以恐惧和回避做出反应的倾向可被视为一种共同的易感性,它会导致创伤后应激障碍(PTSD)和慢性疼痛的发展。尽管有几项研究考察了PTSD的哪些特定症状(再体验、回避、情感麻木和过度警觉)与慢性疼痛相关,但尚无研究在恐惧回避模型的框架内考虑这种关联。
对714名慢性肌肉骨骼疼痛患者进行了评估。其中,149名患者根据以下纳入标准被选入研究:在疼痛发作前经历过创伤事件(在修订的应激性生活事件筛查问卷的恐惧和绝望量表上得分等于或高于8分),且在戴维森创伤量表上得分等于或高于30分。
采用结构方程模型,使用恐惧回避模型中考虑的中介变量,来检验PTSD症状与疼痛结果(疼痛强度和残疾)之间的关联。结果表明,情感麻木和过度警觉症状,而非再体验和回避症状,通过焦虑敏感性(AS)、灾难化思维和对疼痛的恐惧影响疼痛结果。PTSD症状增加了AS的水平,这易引发灾难化思维,进而影响疼痛患者以更多恐惧和回避做出反应的倾向。
本研究为PTSD症状在慢性疼痛的恐惧回避模型中的潜在作用提供了实证支持,并表明AS是这两种疾病之间关系中的一个相关变量。