SAARLAND UNIVERSITY MEDICAL SCHOOL.
Blood. 2014 Mar 27;123(13):1980-1. doi: 10.1182/blood-2014-02-554691.
In this issue of Blood, Yakimchuk and colleagues show that estrogen receptor β (ERβ) signaling can act tumor-suppressive predominantly through the regulation of genes by ERβ in the tumor, not in the microenvironment, and point out new therapeutic strategies.
在本期《Blood》杂志中,Yakimchuk 及其同事表明,雌激素受体β(ERβ)信号主要通过 ERβ 在肿瘤而非微环境中对基因的调节发挥肿瘤抑制作用,并指出了新的治疗策略。