肝移植受者中与产肺炎克雷伯菌碳青霉烯酶2的肺炎克雷伯菌相关的超额死亡率的经验教训。 - Suppr

Lessons learned from excess mortality associated with Klebsiella pneumoniae carbapenemase 2-producing K. pneumoniae in liver transplant recipients.

作者信息

Lübbert Christoph, Rodloff Arne C, Laudi Sven, Simon Philipp, Busch Thilo, Mössner Joachim, Bartels Michael, Kaisers Udo X

机构信息

Division of Infectious Diseases and Tropical Medicine Department of Gastroenterology and Rheumatology, Leipzig University Hospital, Leipzig, Germany.

出版信息

Liver Transpl. 2014 Jun;20(6):736-8. doi: 10.1002/lt.23858. Epub 2014 Mar 26.

DOI:10.1002/lt.23858

PMID:24677425

Abstract

摘要

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Lessons learned from excess mortality associated with Klebsiella pneumoniae carbapenemase 2-producing K. pneumoniae in liver transplant recipients.肝移植受者中与产肺炎克雷伯菌碳青霉烯酶2的肺炎克雷伯菌相关的超额死亡率的经验教训。

Liver Transpl. 2014 Jun;20(6):736-8. doi: 10.1002/lt.23858. Epub 2014 Mar 26.

Infection with Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae in solid organ transplantation.实体器官移植中感染产肺炎克雷伯菌碳青霉烯酶（KPC）的肺炎克雷伯菌。

Transpl Infect Dis. 2012 Apr;14(2):198-205. doi: 10.1111/j.1399-3062.2011.00688.x. Epub 2011 Oct 28.

Intercontinental spread from Israel to Colombia of a KPC-3-producing Klebsiella pneumoniae strain.以色列至哥伦比亚产 KPC-3 肺炎克雷伯菌的洲际传播。

Clin Microbiol Infect. 2011 Jan;17(1):52-6. doi: 10.1111/j.1469-0691.2010.03209.x.

An outbreak of infection due to beta-Lactamase Klebsiella pneumoniae Carbapenemase 2-producing K. pneumoniae in a Greek University Hospital: molecular characterization, epidemiology, and outcomes.希腊某大学医院产碳青霉烯酶肺炎克雷伯菌β-内酰胺酶 2 的肺炎克雷伯菌感染暴发：分子特征、流行病学和结局。

Clin Infect Dis. 2010 Feb 1;50(3):364-73. doi: 10.1086/649865.

Successful containment and infection control of a Carbapenem-resistant Klebsiella pneumoniae outbreak in an Italian hospital.意大利一家医院成功控制耐碳青霉烯类肺炎克雷伯菌暴发及感染防控

New Microbiol. 2014 Jan;37(1):87-90. Epub 2014 Jan 15.

Outbreak due to a Klebsiella pneumoniae strain harbouring KPC-2 and VIM-1 in a German university hospital, July 2010 to January 2011.2010 年 7 月至 2011 年 1 月，德国一家大学医院暴发由携带 KPC-2 和 VIM-1 的肺炎克雷伯菌引起的疫情。

Euro Surveill. 2011 Aug 18;16(33):19944.

Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae: a review of epidemiological and clinical aspects.产碳青霉烯酶肺炎克雷伯菌（KPC）肺炎克雷伯菌：流行病学和临床方面的综述。

Expert Opin Biol Ther. 2012 Jun;12(6):663-71. doi: 10.1517/14712598.2012.681369. Epub 2012 Apr 16.

Outcomes of transplantation using organs from a donor infected with Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae.使用感染产肺炎克雷伯菌碳青霉烯酶（KPC）的肺炎克雷伯菌供体器官进行移植的结果。

Transpl Infect Dis. 2012 Jun;14(3):229-36. doi: 10.1111/j.1399-3062.2012.00742.x. Epub 2012 May 25.

Bloodstream infections due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae: risk factors for mortality and treatment outcome, with special emphasis on antimicrobial therapy.产超广谱β-内酰胺酶大肠埃希菌和肺炎克雷伯菌引起的血流感染：死亡率和治疗结果的危险因素，特别强调抗菌治疗。

Antimicrob Agents Chemother. 2004 Dec;48(12):4574-81. doi: 10.1128/AAC.48.12.4574-4581.2004.

Mortality associated with carbapenem-resistant Klebsiella pneumoniae infections in liver transplant recipients.肝移植受者中耐碳青霉烯类肺炎克雷伯菌感染相关的死亡率。

Liver Transpl. 2012 Apr;18(4):468-74. doi: 10.1002/lt.23374.

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Carbapenem-resistant infections after liver transplantation: Drug resistance, risk factors and impact on prognosis.肝移植术后耐碳青霉烯类感染：耐药性、危险因素及对预后的影响

World J Gastroenterol. 2025 Feb 28;31(8):98415. doi: 10.3748/wjg.v31.i8.98415.

infections after liver transplantation: Drug resistance and distribution of pathogens, risk factors, and influence on outcomes.肝移植术后感染：病原体的耐药性与分布、危险因素及对预后的影响

World J Hepatol. 2024 Apr 27;16(4):612-624. doi: 10.4254/wjh.v16.i4.612.

New Antibiotics Against Multidrug-Resistant Gram-Negative Bacteria in Liver Transplantation: Clinical Perspectives, Toxicity, and PK/PD Properties.新型抗多重耐药革兰氏阴性菌抗生素在肝移植中的临床应用、毒性和药代动力学/药效学特性。

Transpl Int. 2024 Feb 1;37:11692. doi: 10.3389/ti.2024.11692. eCollection 2024.

A Proposal for a Classification Guiding the Selection of Appropriate Antibiotic Therapy for Intra-Abdominal Infections.关于指导腹腔内感染合适抗生素治疗选择的分类建议

Antibiotics (Basel). 2022 Oct 12;11(10):1394. doi: 10.3390/antibiotics11101394.

WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections.WSES/GAIS/SIS-E/WSIS/AAST 全球腹腔内感染患者临床路径。

World J Emerg Surg. 2021 Sep 25;16(1):49. doi: 10.1186/s13017-021-00387-8.

Risk Factors and Outcomes of Carbapenem-Resistant Enterobacteriaceae Infection After Liver Transplantation: A Retrospective Study in a Chinese Population.肝移植术后耐碳青霉烯类肠杆菌科细菌感染的危险因素及结局：一项中国人群的回顾性研究

Infect Drug Resist. 2020 Nov 10;13:4039-4045. doi: 10.2147/IDR.S278084. eCollection 2020.

Prevalence, Risk Factors And Treatment Of The Most Common Gram-Negative Bacterial Infections In Liver Transplant Recipients: A Review.肝移植受者中最常见革兰氏阴性菌感染的患病率、危险因素及治疗：综述

Infect Drug Resist. 2019 Nov 13;12:3485-3495. doi: 10.2147/IDR.S226217. eCollection 2019.

The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections.从全球视角看腹腔内感染的管理：2017 年 WSES 腹腔内感染管理指南。

World J Emerg Surg. 2017 Jul 10;12:29. doi: 10.1186/s13017-017-0141-6. eCollection 2017.

Environmental pollution with antimicrobial agents from bulk drug manufacturing industries in Hyderabad, South India, is associated with dissemination of extended-spectrum beta-lactamase and carbapenemase-producing pathogens.印度南部海得拉巴大宗原料药制造行业的抗菌剂环境污染，与产超广谱β-内酰胺酶和碳青霉烯酶病原体的传播有关。

Infection. 2017 Aug;45(4):479-491. doi: 10.1007/s15010-017-1007-2. Epub 2017 Apr 26.

Carbapenem-resistant Enterobacteriaceae in special populations: Solid organ transplant recipients, stem cell transplant recipients, and patients with hematologic malignancies.特殊人群中的耐碳青霉烯肠杆菌科：实体器官移植受者、造血干细胞移植受者和血液恶性肿瘤患者。

Virulence. 2017 May 19;8(4):391-402. doi: 10.1080/21505594.2016.1213472. Epub 2016 Jul 28.

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Lessons learned from excess mortality associated with Klebsiella pneumoniae carbapenemase 2-producing K. pneumoniae in liver transplant recipients.

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