Chacón J L, Assayag M S, Revolledo L, Astolfi-Ferreira C S, Vejarano M P, Jones R C, Piantino Ferreira A J
a Department of Pathology , School of Veterinary Medicine - University of São Paulo , Av. Prof. Dr. Orlando M. Paiva, 87, CEP 05508-900 , São Paulo , SP , Brazil.
Br Poult Sci. 2014;55(3):271-83. doi: 10.1080/00071668.2014.903558.
Abstract 1. The possibility that infectious bronchitis virus (IBV) variants isolated from broilers with enteric and respiratory problems have a different tropism and pathological outcome from those IBV strains causing classical respiratory disease was investigated. 2. IBV variants were isolated from broiler flocks with enteric and respiratory problems in two regions of Brazil. The USP-10 isolate, of enteric origin, was inoculated via the oral oroculonasal routes into IBV-antibody-free broilers and specific pathogen-free (SPF) chickens to determine tissue tropism and pathogenicity and compared with an IBV variant (USP-50) isolated from chickens showing signs of respiratory disease only. 3. Both USP-10 and USP-50 strains caused similar pathological patterns by either route of inoculation. Both variants were detected in respiratory and non-respiratory tissues, including the kidney, intestine and testis. 4. Broilers were more susceptible to infection than SPF chickens, and seroconversion was detected in all of the chicks.
摘要 1. 研究了从患有肠道和呼吸道问题的肉鸡中分离出的传染性支气管炎病毒（IBV）变体与引起经典呼吸道疾病的IBV毒株相比，是否具有不同的嗜性和病理结果。2. 从巴西两个地区患有肠道和呼吸道问题的肉鸡群中分离出IBV变体。将源自肠道的USP-10分离株通过口服或口鼻途径接种到无IBV抗体的肉鸡和无特定病原体（SPF）鸡中，以确定组织嗜性和致病性，并与仅从表现出呼吸道疾病迹象的鸡中分离出的IBV变体（USP-50）进行比较。3. USP-10和USP-50毒株通过任何一种接种途径都引起相似的病理模式。在包括肾脏、肠道和睾丸在内的呼吸道和非呼吸道组织中均检测到这两种变体。4. 肉鸡比SPF鸡更容易感染，并且在所有雏鸡中均检测到血清转化。
