Tanaka Yoko, Yamada Hiroyuki, Saito Tomoyuki, Nakaoka Kazutoshi, Kumagai Kenichi, Fujihara Hisako, Mishima Kenji, Hamada Yoshiki
Department of Oral and Maxillofacial Surgery, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, Japan.
World J Surg Oncol. 2014 Mar 28;12:69. doi: 10.1186/1477-7819-12-69.
Myofibroma is a benign tumor composed of myoid spindle cells. The prevalence of myofibroma in the oral cavity is very low, with the mandible being the most common site. This report describes an adult case of myofibroma that arose on the mandible and includes magnetic resonance imaging (MRI) and positron emission tomography (PET) findings. On the MRI T1-weighted images, the tumor appeared with signal iso-intensity and was highly and heterogeneously enhanced with contrast material. On the T2-weighted images, it appeared with increased signal intensity. 18 F-fluorodeoxyglucose (FDG)-PET imaging showed abnormal strong accumulation of FDG in the left mandibular region. The tumor was removed by marginal resection of the left mandible under general anesthesia. Histopathological findings revealed that the tumor stroma contained abundant thin-walled vessels. The postoperative course was uneventful, and we found no evidence of recurrence at the postoperative 34-month follow-up.
肌纤维瘤是一种由肌样梭形细胞组成的良性肿瘤。口腔肌纤维瘤的患病率很低，下颌骨是最常见的发病部位。本报告描述了一例发生在下颌骨的成人肌纤维瘤病例，并包括磁共振成像（MRI）和正电子发射断层扫描（PET）检查结果。在MRI T1加权图像上，肿瘤呈等信号强度，注射造影剂后呈高度不均匀强化。在T2加权图像上，肿瘤信号强度增加。18F-氟脱氧葡萄糖（FDG）-PET成像显示左下颌骨区域有异常强烈的FDG摄取。在全身麻醉下对左下颌骨进行边缘性切除，将肿瘤切除。组织病理学检查结果显示肿瘤间质内含有丰富的薄壁血管。术后病程顺利，术后34个月随访未发现复发迹象。
