Atarbashi-Moghadam Saede, Lotfi Ali, Shahrabi-Farahani Shokoufeh, Atarbashi-Moghadam Fazele
Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Division of Oral and Maxillofacial Pathology, Dept. of Diagnostic Sciences and Oral Medicine, University of Tennessee Health Science Center, College of Dentistry, Memphis, TN.
J Dent (Shiraz). 2018 Jun;19(2):164-167.
Solitary myofibroma is an uncommon benign soft tissue neoplasm of myofibroblastic origin exhibiting head and neck region predilection but its presence in the jaws is rare. Myofibroma presents as painless mass and may demonstrate rapid enlargement and growth that clinically mimic malignancies. This report presents a 4-year-old male patient with a rapidly growing mandibular gingival mass with some evidence of underlying alveolar bone destruction. Incisional biopsy was performed and the specimen was stained with hematoxylin and eosin and immunohistochemical antibodies for αSMA, CD34, S100 and desmin. The diagnosis of myofibroma was made and the lesion was completely excised. The knowledge about microscopic features of this rare neoplasm helps to have a proper diagnosis and avoid unnecessary treatment.
孤立性肌纤维瘤是一种罕见的起源于肌成纤维细胞的良性软组织肿瘤，好发于头颈部，但在颌骨中罕见。肌纤维瘤表现为无痛性肿块，可能会迅速增大，在临床上类似恶性肿瘤。本报告介绍了一名4岁男性患者，其下颌牙龈肿物迅速生长，并有一些潜在牙槽骨破坏的迹象。进行了切开活检，标本用苏木精和伊红染色，并使用针对αSMA、CD34、S100和结蛋白的免疫组化抗体进行检测。诊断为肌纤维瘤，并将病变完全切除。了解这种罕见肿瘤的微观特征有助于做出正确诊断并避免不必要的治疗。
