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女性膀胱颈梗阻行膀胱颈切开术:长期疗效。

Bladder neck incision for female bladder neck obstruction: long-term outcomes.

机构信息

Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

出版信息

Urology. 2014 Apr;83(4):762-6. doi: 10.1016/j.urology.2013.10.084.

Abstract

OBJECTIVE

To evaluate the long-term outcomes of bladder neck incision (BNI) for primary bladder neck obstruction in women.

METHODS

Eighty-four women were diagnosed on the basis of videourodynamic study. BNI was performed for each patient, with incisions made at 2 different sites on the bladder neck.

RESULTS

Follow-up data were available for 6-78 months (average, 27.4), postoperatively. Successful recovery after BNI without serious complications was achieved in 71 of 84 (84.5%) patients. During follow-up, the mean International Prostate Symptom Score decreased from 22.9 to 7.9 (P <.01). Quality of life decreased from 4.1 to 2.4 (P <.01). The maximum uroflow rate increased from 9.75 to 18.79 mL/s (P <.01). The postvoid residual decreased from 115.11 to 23.29 mL (P <.01). The maximal detrusor pressure at the maximum uroflow rate decreased from 69.61 to 20.48 cm H2O (P <.01). Several complications were identified after surgery, including hemorrhage, re-BNI, vesicovaginal fistula (VVF), stress urinary incontinence (SUI), and urethral stricture. All these complications were grade IIIa in the Clavien Classification of Surgical Complications. Three patients (3.6%) developed a VVF after BNI; these VVFs were repaired successfully. Four (4.7%) patients experienced SUI and recovered after transvaginal tension-free vaginal tape-obturator. Postoperative bleeding was identified in 3 patients (3.6%), and 1 received a blood transfusion. Three (3.6%) patients experienced urethral stricture after BNI and recovered after receiving intermittent urethral dilation.

CONCLUSION

Primary bladder neck obstruction is uncommon and easily treatable when properly diagnosed by videourodynamic study, and BNI has a high success rate. Careful, sufficiently deep incisions at the 2- and 10-o'clock positions can ensure its success. Complications such as postoperative VVF or SUI can occur and must be actively managed.

摘要

目的

评估膀胱颈切开术(BNI)治疗女性原发性膀胱颈梗阻的长期疗效。

方法

84 名女性基于尿动力学研究诊断为膀胱颈梗阻,每位患者均接受 BNI 治疗,在膀胱颈的 2 个不同部位进行切口。

结果

84 名患者中有 71 名(84.5%)术后获得成功恢复,无严重并发症。84 名患者的平均随访时间为 6-78 个月(27.4 个月)。BNI 后,国际前列腺症状评分从 22.9 降至 7.9(P<.01),生活质量评分从 4.1 降至 2.4(P<.01),最大尿流率从 9.75 升至 18.79ml/s(P<.01),残余尿量从 115.11 降至 23.29ml(P<.01),最大尿流率时逼尿肌压力从 69.61 降至 20.48cmH2O(P<.01)。术后发现多种并发症,包括出血、再次 BNI、膀胱阴道瘘(VVF)、压力性尿失禁(SUI)和尿道狭窄。所有这些并发症在外科并发症的 Clavien 分类中均为 IIIa 级。3 名患者(3.6%)在 BNI 后发生 VVF,均成功修复。4 名患者(4.7%)发生 SUI,经阴道无张力阴道吊带-闭孔器治疗后恢复。3 名患者(3.6%)术后出血,1 例输血。3 名患者(3.6%)在 BNI 后发生尿道狭窄,经间歇性尿道扩张后恢复。

结论

原发性膀胱颈梗阻并不常见,通过尿动力学研究正确诊断后,可有效治疗,BNI 成功率高。在 2 点和 10 点位置仔细、充分地切开,可确保手术成功。术后 VVF 或 SUI 等并发症可能发生,必须积极处理。

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