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女性原发性膀胱颈梗阻的治疗:膀胱颈切开术是最佳治疗方法吗?

Managing Primary Bladder Neck Obstruction in Females: Is Bladder Neck Incision the Best Way Forward?

作者信息

Bhatia Skandh, Kurmi Narendra, Vyas Sameer, Jain Saurabh, Jain Amit, Kumar Saurabh, Jani Ajaybhai, Singh Mehta Gursharan

机构信息

Department of Urology, Gandhi Medical College, Bhopal, Bhopal, IND.

Department of Community Medicine, Gandhi Medical College, Bhopal, Bhopal, IND.

出版信息

Cureus. 2025 Apr 25;17(4):e82976. doi: 10.7759/cureus.82976. eCollection 2025 Apr.

Abstract

Background Primary bladder neck obstruction (PBNO) in females is a rare condition with a tedious diagnostic process. The existing literature on bladder neck incision (BNI) to treat PBNO lacks a precise description of the surgical technique. Objective In this study, we provide a diagnostic protocol to streamline the evaluation of PBNO in females. We evaluate the outcomes of a precise surgical technique of BNI aimed at reducing the rates of known complications such as vesicovaginal fistula (VVF) and urinary incontinence. Methods This single-center prospective observational study, conducted over five years (2019-2024), included 20 patients diagnosed with PBNO who underwent BNI. Analyses included patient demographics, clinical presentation, treatment outcomes, and complications. Statistical analysis was performed using ANOVA, and univariate analysis was also conducted. Differences with P < 0.05 were considered statistically significant. Results At six months post-surgery, the mean maximum urinary flow rate (Qmax) increased from 6.49 ± 2.63 mL/sec to 12.41 ± 2.42 mL/sec (P = 0.0421). The mean post-void residual volume (PVR) decreased from 202.11 ± 70.20 mL to 53.11 ± 14.78 mL (P = 0.0152). The mean International Prostate Symptom Score (IPSS) decreased from 26.95 ± 2.84 to 14.74 ± 3.23 (P = 0.0325). The mean quality of life (QoL) score improved from 4.70 ± 0.80 to 1.60 ± 0.12 (P = 0.0067). None of the patients developed VVF or urinary incontinence in the post-operative period. One patient (5%) required re-surgery due to recurrence of bladder neck obstruction. Conclusion BNI for PBNO provides satisfactory results. A precise operative technique, with careful consideration of the depth and distal extent of the incision, helps avoid complications such as VVF and urinary incontinence.

摘要

背景 女性原发性膀胱颈梗阻(PBNO)是一种罕见疾病,诊断过程繁琐。现有关于膀胱颈切开术(BNI)治疗PBNO的文献缺乏对手术技术的精确描述。目的 在本研究中,我们提供一种诊断方案,以简化对女性PBNO的评估。我们评估一种精确的BNI手术技术的效果,旨在降低诸如膀胱阴道瘘(VVF)和尿失禁等已知并发症的发生率。方法 这项为期五年(2019 - 2024年)的单中心前瞻性观察性研究纳入了20例诊断为PBNO并接受BNI的患者。分析内容包括患者人口统计学、临床表现、治疗效果和并发症。使用方差分析进行统计分析,并进行单因素分析。P < 0.05的差异被认为具有统计学意义。结果 术后六个月,平均最大尿流率(Qmax)从6.49 ± 2.63 mL/秒增加到12.41 ± 2.42 mL/秒(P = 0.0421)。平均排尿后残余尿量(PVR)从202.11 ± 70.20 mL降至53.11 ± 14.78 mL(P = 0.0152)。平均国际前列腺症状评分(IPSS)从26.95 ± 2.84降至14.74 ± 3.23(P = 0.0325)。平均生活质量(QoL)评分从4.70 ± 0.80提高到1.60 ± 0.12(P = 0.0067)。术后期间无患者发生VVF或尿失禁。1例患者(5%)因膀胱颈梗阻复发需要再次手术。结论 BNI治疗PBNO可提供满意结果。一种精确的手术技术,仔细考虑切口的深度和远端范围,有助于避免诸如VVF和尿失禁等并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f78b/12103814/0fa2accd310e/cureus-0017-00000082976-i01.jpg

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