Chippaux Jean-Philippe, Postigo Jorge R
UMR 216, Mother and Child Facing Tropical Diseases, Institut de Recherche pour le Développement (IRD), La Paz, Bolivia; Université Paris Descartes, Sorbonne Paris Cité, Faculté de Pharmacie, France; Laboratorio de Parasitología, Instituto Nacional de Laboratorios de Salud (INLASA), Ministerio de Salud y Deportes, La Paz, Bolivia.
UMR 216, Mother and Child Facing Tropical Diseases, Institut de Recherche pour le Développement (IRD), La Paz, Bolivia.
Toxicon. 2014 Jun;84:28-35. doi: 10.1016/j.toxicon.2014.03.007. Epub 2014 Mar 27.
No information has been yet published on snakebite in Bolivia. The country includes very different ecological situations leading to various epidemiological risks. A study has been carried out to evaluate the incidence and location of snakebite, particularly in relation with altitude, in order to improve management. Investigations on snakebite epidemiology were based on a) cases treated in health facilities as reported by health authorities and b) household surveys carried out in areas with high variations of altitude, in various regions of Bolivia. An average of 700 bites was treated each year in Bolivia (national annual incidence = 8 bites per 100,000 people) with a great disparity between districts. Household surveys showed annual incidences ranged from 30 to 110 bites per 100,000 inhabitants depending on location. Annual mortality ranged 0.1-3.9 per 100,000 people. A significant and constant inverse correlation was shown between snakebite incidence and altitude, which may be explained by both snake and human distributions and activities. Notification of snakebite is useful for improving patient management and informing antivenom distribution. It should also involve the report of deaths and clinical details of envenomation.
关于玻利维亚蛇咬伤情况,目前尚未有信息发表。该国生态情况差异极大,导致了各种不同的流行病学风险。为了改进管理措施,已开展一项研究来评估蛇咬伤的发病率及发生地点,特别是与海拔高度的关系。蛇咬伤流行病学调查基于以下两方面:a) 卫生当局报告的在医疗机构接受治疗的病例;b) 在玻利维亚不同地区海拔高度变化较大的区域开展的家庭调查。玻利维亚每年平均治疗700例咬伤病例(全国年发病率为每10万人中有8例咬伤),各地区之间存在很大差异。家庭调查显示,根据地点不同,年发病率在每10万居民30至110例咬伤之间。年死亡率为每10万人0.1至3.9例。蛇咬伤发病率与海拔高度之间呈现出显著且持续的负相关,这可能是由蛇类分布以及人类活动共同导致的。蛇咬伤报告对于改善患者管理及指导抗蛇毒血清的分发很有帮助。报告还应包含死亡情况及蛇毒中毒的临床细节。