Rantala S
Department of Internal Medicine, Tampere University Hospital, P.O. Box 2000, 33521, Tampere, Finland,
Eur J Clin Microbiol Infect Dis. 2014 Aug;33(8):1303-10. doi: 10.1007/s10096-014-2092-0. Epub 2014 Mar 29.
The importance of group C and G Streptococcus dysgalactiae subspecies equisimilis (S. dysgalactiae subsp. equisimilis) as a significant pathogen has recently been better recognized. S. dysgalactiae subsp. equisimilis disease can range in severity from milder skin and soft-tissue conditions such as wound infection, erysipelas, and cellulitis, to life-threatening necrotizing fasciitis and streptococcal toxic shock syndrome, thus sharing the clinical picture with S. pyogenes. The most common clinical manifestation of bacteremia is cellulitis. An increase in the incidence of S. dysgalactiae subsp. equisimilis bacteremia has been recognized. Invasive forms of this infection are most commonly found in elderly patients with underlying comorbidities and skin breakdown. The case fatality in bacteremia has been reported to be 15-18%. In this review, the epidemiology, clinical characteristics, and emm types of S. dysgalactiae subsp. equisimilis bacteremia are summarized.
C组和G组似马链球菌（马链球菌兽疫亚种）作为一种重要病原体的重要性近来已得到更好的认识。马链球菌兽疫亚种疾病的严重程度不一，从较轻的皮肤和软组织病症，如伤口感染、丹毒和蜂窝织炎，到危及生命的坏死性筋膜炎和链球菌中毒性休克综合征，因此与化脓性链球菌有相似的临床表现。菌血症最常见的临床表现是蜂窝织炎。已认识到马链球菌兽疫亚种菌血症的发病率有所增加。这种感染的侵袭性形式最常见于有基础合并症和皮肤破损的老年患者。据报道，菌血症的病死率为15% - 18%。在本综述中，总结了马链球菌兽疫亚种菌血症的流行病学、临床特征和emm型。
