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Elimination of undifferentiated cancer cells by pluripotent stem cell inhibitors.

作者信息

Ben-David Uri, Biran Alva, Scaffidi Paola, Herold-Mende Christel, Boehringer Markus, Meshorer Eran, Benvenisty Nissim

机构信息

Stem Cell Unit, Silberman Institute of Life Sciences, The Hebrew University, Jerusalem 91904, Israel Department of Genetics, Silberman Institute of Life Sciences, The Hebrew University, Jerusalem 91904, Israel.

Department of Genetics, Silberman Institute of Life Sciences, The Hebrew University, Jerusalem 91904, Israel.

出版信息

J Mol Cell Biol. 2014 Jun;6(3):267-9. doi: 10.1093/jmcb/mju012. Epub 2014 Mar 27.

DOI:10.1093/jmcb/mju012
PMID:24683201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4055828/
Abstract
摘要

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本文引用的文献

1
Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen.高通量筛选中发现的一种油酸合成抑制剂可选择性消除人多能干细胞。
Cell Stem Cell. 2013 Feb 7;12(2):167-79. doi: 10.1016/j.stem.2012.11.015. Epub 2013 Jan 11.
2
The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming.诱导多能干细胞的代谢组学揭示了体细胞重编程过程中发生的代谢变化。
Cell Res. 2012 Jan;22(1):168-77. doi: 10.1038/cr.2011.177. Epub 2011 Nov 8.
3
Cancer cell dependence on unsaturated fatty acids implicates stearoyl-CoA desaturase as a target for cancer therapy.癌细胞对不饱和脂肪酸的依赖性表明硬脂酰辅酶 A 去饱和酶是癌症治疗的靶点。
Mol Cancer Res. 2011 Nov;9(11):1551-61. doi: 10.1158/1541-7786.MCR-11-0126. Epub 2011 Sep 27.
4
In vitro generation of human cells with cancer stem cell properties.体外生成具有癌症干细胞特性的人类细胞。
Nat Cell Biol. 2011 Aug 21;13(9):1051-61. doi: 10.1038/ncb2308.
5
The tumorigenicity of human embryonic and induced pluripotent stem cells.人胚胎干细胞和诱导多能干细胞的致瘤性。
Nat Rev Cancer. 2011 Apr;11(4):268-77. doi: 10.1038/nrc3034. Epub 2011 Mar 10.
6
The cancer stem cell: premises, promises and challenges.癌症干细胞：前提、承诺和挑战。
Nat Med. 2011 Mar;17(3):313-9. doi: 10.1038/nm.2304.
7
Inhibition of stearoyl-CoA desaturase 1 expression induces CHOP-dependent cell death in human cancer cells.抑制硬脂酰辅酶 A 去饱和酶 1 的表达可诱导人癌细胞中 CHOP 依赖性细胞死亡。
PLoS One. 2010 Dec 16;5(12):e14363. doi: 10.1371/journal.pone.0014363.
8
Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells.硬脂酰辅酶 A 去饱和酶活性的抑制可阻断肺癌细胞的细胞周期进程并诱导程序性细胞死亡。
PLoS One. 2010 Jun 30;5(6):e11394. doi: 10.1371/journal.pone.0011394.
9
Differentiation therapy exerts antitumor effects on stem-like glioma cells.分化治疗对肿瘤干细胞样细胞发挥抗肿瘤作用。
Clin Cancer Res. 2010 May 15;16(10):2715-28. doi: 10.1158/1078-0432.CCR-09-1800. Epub 2010 May 4.
10
Stem cells, cancer, and cancer stem cells.干细胞、癌症与癌症干细胞。
Nature. 2001 Nov 1;414(6859):105-11. doi: 10.1038/35102167.