Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Utrecht, The Netherlands.
Nat Med. 2011 Mar;17(3):313-9. doi: 10.1038/nm.2304.
Over the last decade, the notion that tumors are maintained by their own stem cells, the so-called cancer stem cells, has created great excitement in the research community. This review attempts to summarize the underlying concepts of this notion, to distinguish hard facts from beliefs and to define the future challenges of the field.
在过去的十年中，肿瘤由其自身的干细胞维持这一观点，即所谓的癌症干细胞，在研究界引起了极大的兴奋。本文试图总结这一观点的基本概念，将事实与观点区分开来，并定义该领域未来的挑战。
