从切迹到胶质瘤分级系统：詹姆斯·沃森·克诺汉的神经学贡献
From the notch to a glioma grading system: the neurological contributions of James Watson Kernohan.
作者信息
Safavi-Abbasi Sam, Maurer Adrian J, Archer Jacob B, Hanel Ricardo A, Sughrue Michael E, Theodore Nicholas, Preul Mark C
机构信息
Department of Neurosurgery, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma;
出版信息
Neurosurg Focus. 2014 Apr;36(4):E4. doi: 10.3171/2014.1.FOCUS13575.
During his lifetime and a career spanning 42 years, James Watson Kernohan made numerous contributions to neuropathology, neurology, and neurosurgery. One of these, the phenomenon of ipsilateral, false localizing signs caused by compression of the contralateral cerebral peduncle against the tentorial edge, has widely become known as "Kernohan's notch" and continues to bear his name. The other is a grading system for gliomas from a neurosurgical viewpoint that continues to be relevant for grading of glial tumors 60 years after its introduction. In this paper, the authors analyze these two major contributions in detail within the context of Kernohan's career and explore how they contributed to the development of neurosurgical procedures.
在其42年的职业生涯中，詹姆斯·沃森·克诺汉对神经病理学、神经病学和神经外科做出了诸多贡献。其中之一，即对侧大脑脚被小脑幕边缘压迫所导致的同侧假性定位体征现象，已广为人知，被称为“克诺汉切迹”，至今仍以他的名字命名。另一个贡献是从神经外科角度提出的胶质瘤分级系统，该系统在引入60年后，对于胶质肿瘤的分级仍然具有重要意义。在本文中，作者在克诺汉的职业生涯背景下详细分析了这两项主要贡献，并探讨了它们如何推动了神经外科手术的发展。
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