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表达一种新型重组融合蛋白 BVN-Tβ4 及其对糖尿病创面愈合的影响。

Expression of a novel recombinant fusion protein BVN-Tβ4 and its effects on diabetic wound healing.

机构信息

School of Life Science and Technology, Shangqiu Normal University, Shangqiu 476000, China.

School of Environment and Planning, Shangqiu Normal University, Shangqiu 476000, China.

出版信息

J Biosci Bioeng. 2014 Sep;118(3):341-3. doi: 10.1016/j.jbiosc.2014.02.022. Epub 2014 Mar 29.

Abstract

A recombinant fusion protein BVN-Tβ4 is successfully expressed in Escherichia coli, purified in the laboratory and applied onto the wounds of diabetic mice to investigate its effects on diabetic wound healing. Our results show that the recombinant protein BVN-Tβ4 can promote diabetic wound healing in the murine model.

摘要

一种重组融合蛋白 BVN-Tβ4 在大肠杆菌中成功表达,经实验室纯化后应用于糖尿病小鼠的伤口,以研究其对糖尿病伤口愈合的影响。结果表明,重组蛋白 BVN-Tβ4 可促进糖尿病小鼠模型的伤口愈合。

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