中国大陆首例荚膜组织胞浆菌感染的检测与系统进化特征分析。
Detection and phylogenetic characterization of a case of Histoplasma capsulatum infection in mainland China.
机构信息
Department of Dermatology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China; Department of Dermatology, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Department of Dermatology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China; Department of Dermatology, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China
出版信息
Am J Trop Med Hyg. 2014 Jun;90(6):1180-3. doi: 10.4269/ajtmh.14-0048. Epub 2014 Mar 31.
Abstract
Histoplasmosis usually occurs in specific endemic areas. Sporadic cases have also been reported in mainland China. Here, we described an indigenous case of disseminated histoplasmosis. Phylogenetic analysis revealed that the Histoplasma capsulatum isolated in our case belongs to the Australian clade. Combined with previous studies, it revealed high genetic diversity among Chinese H. capsulatum isolates.
摘要
组织胞浆菌病通常发生在特定的流行地区。中国大陆也有散发病例报告。在这里，我们描述了一例播散性组织胞浆菌病的本土病例。系统发育分析显示，我们分离的荚膜组织胞浆菌属于澳大利亚分支。结合以往的研究，表明中国荚膜组织胞浆菌分离株具有较高的遗传多样性。
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