Department of Dermatology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Province, People's Republic of China.
Mycopathologia. 2010 Jul;170(1):47-50. doi: 10.1007/s11046-010-9295-4. Epub 2010 Mar 12.
This is the first indigenous case of disseminated histoplasmosis reported from the Penicillium marneffei endemic area in southern China. It was diagnosed by histopathology of tissue, gross and microscopic morphology of the culture and PCR assay of the isolated fungus. Successful antifungal treatment was with itraconazole 400 mg/day for 5 months. This case suggests that histoplasmosis should be an important differential diagnosis in immunocompromised patients in southern China and South East Asia (the only endemic area for P. marneffei).
这是首例从中国南方马尔尼菲青霉菌流行地区报告的播散性组织胞浆菌病的本土病例。通过组织病理学、培养的大体和显微镜形态以及分离真菌的 PCR 检测进行了诊断。成功的抗真菌治疗是使用伊曲康唑每天 400 毫克，治疗 5 个月。该病例提示在免疫功能低下的患者中，组织胞浆菌病应作为中国南方和东南亚（唯一的马尔尼菲青霉菌流行地区）的重要鉴别诊断。
