Xu Jian, Zeng Guang-Zhi, Chen Ke-Li, Liu Yi-Mei, Sun Zhang-Hua, Tan Ning-Hua, Zhang Yu-Mei
Nat Prod Commun. 2014 Feb;9(2):215-6.
A new lignan glycoside, (-)-(8S, 8'R)-thujastandin-4-O-beta-D-glucopyranoside (1), together with fourteen known lignanoids (2-15) and one coumarin (16) were isolated from the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii. Their structures were elucidated by extensive spectroscopic and spectrometric analysis. Compound 16 exhibited cytotoxicity against A549, BGC-823 and Hela cell lines with IC50 values of 25.9, 20.9 and 18.5 microM, respectively.
从日本扁柏短叶变种克里普斯氏变型的枝叶中分离得到一种新的木脂素糖苷，(-)-(8S, 8'R)-土荆皮定-4-O-β-D-吡喃葡萄糖苷(1)，以及14种已知的木脂素类化合物(2 - 15)和一种香豆素(16)。通过广泛的光谱和波谱分析确定了它们的结构。化合物16对A549、BGC - 823和Hela细胞系具有细胞毒性，IC50值分别为25.9、20.9和18.5 microM。
