State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Heilongtan, Kunming 650201, China.
Molecules. 2013 Jan 18;18(1):1255-61. doi: 10.3390/molecules18011255.
A new phenolic glycoside, 3-methoxyphenol 1-O-α-L-rhamnopyranosyl-(1→6)- O-β-D-glucopyranoside (1), was isolated from the 90% acetone extract of the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii along with another 10 known phenolics 2-11. Their structures were determined mainly by means of MS, 1D- and 2D-NMR data. Cytotoxicities of compounds 3 and 5-11 were tested on BGC-823, Hela and A549 cancer cell lines, the results showed that compound 8 was bioactive and its IC(50) values were 6.9, 29.7 and 52.9 μM, respectively.
从柏科扁柏属圆柏变种翠柏的 90%丙酮提取物中分离得到一个新的酚糖苷化合物 3-甲氧基苯酚 1-O-α-L-鼠李吡喃糖基-(1→6)-O-β-D-吡喃葡萄糖苷（1），此外还分离得到另外 10 个已知的酚类化合物 2-11。它们的结构主要通过 MS、1D 和 2D-NMR 数据确定。对化合物 3 和 5-11 进行 BGC-823、Hela 和 A549 癌细胞系的细胞毒性测试，结果表明化合物 8 具有生物活性，其 IC50值分别为 6.9、29.7 和 52.9 μM。
