Navarro de Souza Alicia, Groleau Danielle, Loiselle Carmen G, Foulkes William D, Wong Nora
1Federal University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
Qual Health Res. 2014 May;24(5):665-81. doi: 10.1177/1049732314528756. Epub 2014 Apr 1.
We explored the experiences of Ashkenazi Jewish and French Canadian women and meanings attributed to their hereditary breast and ovarian cancer (HBOC) risk. We purposively sampled 40 BRCA1 or BRCA2 (BRCA) mutation carriers and conducted theoretically driven semistructured interviews. According to content analysis, participants from these two ethnocultural groups held divergent meanings associated with being a BRCA carrier and different views pertaining to the illness experience and risk awareness. All participants identified a genetic basis; however, the French Canadian women also expressed other causes. The French Canadian women reported not knowing other carriers in their social environment, whereas the Ashkenazi Jewish women emphasized a strong sense of community contributing to their ethnic risk awareness. Based on these findings, we suggest that French Canadian women could benefit from greater awareness of the HBOC genetic risk and that health care providers should consider ethnically related and individual-based experiences and meanings during counseling.
我们探究了德系犹太裔和法裔加拿大女性的经历，以及她们对遗传性乳腺癌和卵巢癌（HBOC）风险的认知。我们有目的地抽取了40名BRCA1或BRCA2（BRCA）基因突变携带者，并进行了理论驱动的半结构化访谈。根据内容分析，这两个种族文化群体的参与者对于成为BRCA携带者有着不同的认知，对疾病经历和风险意识也有不同的看法。所有参与者都确定了遗传基础；然而，法裔加拿大女性也提到了其他病因。法裔加拿大女性表示在她们的社交圈子里不认识其他携带者，而德系犹太裔女性则强调强烈的社区意识有助于她们了解种族风险。基于这些发现，我们建议法裔加拿大女性可以从提高对HBOC遗传风险的认识中受益，并且医疗保健提供者在咨询过程中应考虑种族相关及基于个体的经历和认知。
