Roberts Christine L, Nicholl Michael C, Algert Charles S, Ford Jane B, Morris Jonathan M, Chen Jian Sheng
Clinical and Population Perinatal Health Research, Kolling Institute, University of Sydney, Sydney, New South Wales, Australia.
BMC Pregnancy Childbirth. 2014 Apr 3;14:125. doi: 10.1186/1471-2393-14-125.
Guidelines recommend that, in the absence of compelling medical indications (low risk) elective caesarean section should occur after 38 completed weeks gestation. However, implementation of these guidelines will mean some women go into labour before the planned date resulting in an intrapartum caesarean section. The aim of this study was to determine the rate at which low-risk women planned for repeat caesarean section go into spontaneous labour before 39 weeks.
We conducted a population-based cohort study of women who were planned to have an elective repeat caesarean section (ERCS) at 39-41 weeks gestation in New South Wales Australia, 2007-2010. Labour, delivery and health outcome information was obtained from linked birth and hospital records for the entire population. Women with no pre-existing medical or pregnancy complications were categorized as 'low risk'. The rate of spontaneous labour before 39 weeks was determined and variation in the rate for subgroups of women was examined using univariate and multivariate analysis.
Of 32,934 women who had ERCS as the reported indication for caesarean section, 17,314 (52.6%) were categorised as 'low-risk'. Of these women, 1,473 (8.5% or 1 in 12) had spontaneous labour or prelabour rupture of the membranes before 39 weeks resulting in an intrapartum caesarean section. However the risk of labour <39 weeks varied depending on previous delivery history: 25% (1 in 4) for those with spontaneous preterm labour in a prior pregnancy; 15% (1 in 7) for women with a prior planned preterm birth (by labour induction or prelabour caesarean) and 6% (1 in 17) among those who had only previously had a planned caesarean section at term. Smoking in pregnancy was also associated with spontaneous labour. Women with spontaneous labour prior to a planned CS in the index pregnancy were at increased risk of out-of-hours delivery, and maternal and neonatal morbidity.
These findings allow clinicians to more accurately determine the likelihood that a planned caesarean section may become an intrapartum caesarean section, and to advise their patients accordingly.
指南建议,在没有令人信服的医学指征(低风险)的情况下,择期剖宫产应在妊娠38周整之后进行。然而,实施这些指南意味着一些女性会在计划日期前发动分娩,从而导致产时剖宫产。本研究的目的是确定计划进行再次剖宫产的低风险女性在39周前自然发动分娩的发生率。
我们对2007年至2010年在澳大利亚新南威尔士州计划在妊娠39至41周进行择期再次剖宫产(ERCS)的女性进行了一项基于人群的队列研究。通过将出生记录与医院记录相链接,获取了整个人群的分娩、接生及健康结局信息。没有既往内科或妊娠并发症的女性被归类为“低风险”。确定了39周前自然发动分娩的发生率,并使用单因素和多因素分析研究了不同亚组女性发生率的差异。
在报告剖宫产指征为ERCS的32934名女性中,17314名(52.6%)被归类为“低风险”。在这些女性中,1473名(8.5%或1/12)在39周前自然发动分娩或胎膜早破,导致产时剖宫产。然而,<39周分娩的风险因既往分娩史而异:既往有自发性早产的女性为25%(1/4);既往有计划早产(引产或临产前剖宫产)的女性为15%(1/7),而既往仅在足月时有计划剖宫产的女性为6%(1/17)。孕期吸烟也与自然发动分娩有关。在本次妊娠计划剖宫产之前自然发动分娩的女性,非工作时间分娩、孕产妇及新生儿发病的风险增加。
这些发现使临床医生能够更准确地确定计划剖宫产可能转变为产时剖宫产的可能性,并据此向患者提供建议。