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Manipulation of T-cell responses with monoclonal antibodies.

作者信息

Waldmann H

机构信息

Department of Pathology, University of Cambridge, United Kingdom.

出版信息

Annu Rev Immunol. 1989;7:407-44. doi: 10.1146/annurev.iy.07.040189.002203.

DOI:10.1146/annurev.iy.07.040189.002203
PMID:2469440
Abstract
摘要

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Manipulation of T-cell responses with monoclonal antibodies.用单克隆抗体调控T细胞反应。
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Monoclonal antibodies to murine CD3 epsilon define distinct epitopes, one of which may interact with CD4 during T cell activation.针对小鼠CD3ε的单克隆抗体可定义不同的表位，其中一个表位可能在T细胞活化过程中与CD4相互作用。
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