Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan; Division of Chest Surgery, Center of Respiratory Medicine, Ohta Nishinouchi Hospital, Koriyama, Japan.
Division of Chest Surgery, Center of Respiratory Medicine, Ohta Nishinouchi Hospital, Koriyama, Japan.
Ann Thorac Surg. 2014 Apr;97(4):e105-7. doi: 10.1016/j.athoracsur.2013.12.069.
Secondary immune thrombocytopenia is a rare paraneoplastic syndrome of lung cancer. We report a case of pulmonary pleomorphic carcinoma with newly diagnosed secondary immune thrombocytopenia. On referral, the patient's complete blood cell count was normal; however, it showed marked thrombocytopenia after 1 month. Blood biochemistry and bone marrow puncture showed normal findings. We speculated that he had immune thrombocytopenia associated with the lung cancer and planned lung resection. Sleeve middle and lower lobectomy was successfully performed with preoperative intravenous immunoglobulin and intraoperative platelet transfusion. His platelet count was restored and maintained a normal level at 8 months after the operation.
继发性免疫性血小板减少症是肺癌罕见的副瘤综合征。我们报告了一例肺多形性癌伴新发继发性免疫性血小板减少症的病例。初诊时,患者的全血细胞计数正常,但 1 个月后出现明显的血小板减少症。血液生化和骨髓穿刺均未见异常。我们推测他患有与肺癌相关的免疫性血小板减少症,并计划进行肺癌切除术。术前静脉注射免疫球蛋白和术中血小板输注,成功进行了袖状中、下肺叶切除术。术后 8 个月,他的血小板计数恢复并维持在正常水平。