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肺腺癌并发副肿瘤性 Evans 综合征 1 例报告。

Paraneoplastic Evans syndrome in a patient with adenocarcinoma of the lung: A case report.

机构信息

Department of Hematology, Tianjin Medical University General Hospital, Tianjin, China.

出版信息

Thorac Cancer. 2017 Jan;8(1):57-60. doi: 10.1111/1759-7714.12398. Epub 2016 Nov 16.

Abstract

We present a rare case of newly diagnosed Evans syndrome associated with lung papillary adenocarcinoma in which the patient showed prompt restoration of blood cell count and long-lasting complete remission of Evans syndrome after lung cancer resection. Detailed investigation led to a diagnosis of Evans syndrome. In the first year of the disease, left lower lung papillary adenocarcinoma was diagnosed. Pulmonary lobectomy and three courses of chemotherapy were performed. Six months after the initial visit, the primary lung cancer and the autoimmune diseases appeared to be well controlled. We hypothesized that our patient's initial presentation of hematological manifestation was a paraneoplastic phenomenon associated to her underlying malignancy. This rare case report illustrates the unique relationship between primary lung cancer and the development of paraneoplastic Evans syndrome.

摘要

我们报告了一例罕见的新发 Evans 综合征伴肺乳头状腺癌病例,患者在肺癌切除术后,血细胞计数迅速恢复,Evans 综合征长期完全缓解。详细的调查导致 Evans 综合征的诊断。疾病的第一年,诊断为左下肺乳头状腺癌。进行了肺叶切除术和三个疗程的化疗。初次就诊后 6 个月,原发性肺癌和自身免疫性疾病似乎得到了很好的控制。我们假设患者最初的血液学表现是一种副瘤现象,与她潜在的恶性肿瘤有关。这个罕见的病例报告说明了原发性肺癌与副瘤性 Evans 综合征发展之间的独特关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1ab/5217919/617838a2a3ff/TCA-8-57-g001.jpg

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