Erfurt L, Kröger C B
IFT Gesundheitsförderung Gesellschaft mbH, München.
Gesundheitswesen. 2015 Feb;77(2):74-80. doi: 10.1055/s-0034-1367039. Epub 2014 Apr 2.
This study examined the acceptance, use and -adherence with regard to stop-smoking medication in addition to a smoking cessation programme. In a multi-centre field study with quasi-experimental control group design, the participants of a smoking cessation programme were asked about their smoking behaviour at the beginning and at the end of the course. A sample of 1 319 participants was contacted via telephone one year after the end of the course. Among the 1 052 participants, who could be interviewed, 312 subjects (29.7%) reported to have used stop-smoking medication while 85.2% of the medication users preferred nicotine replacement therapy. The objective medication adherence was 13.2%. 79.3% of the medication users believed that they had used the medication adherently. There were no significant differences between participants who started use of medication and non-users (long-term abstinence rate: no medication 34.6% vs. medication 31.7%; p=0.34). The outcome of a modern smoking cessation group programme could not be improved by providing additional stop-smoking medication. This finding and the lack of medication adherence raise doubts about the effectiveness of offering stop-smoking medication in addition to an intensive cognitive-behavioural-based smoking cessation programme that focusses on behavioural changes.
本研究除了调查戒烟计划外,还考察了戒烟药物的接受情况、使用情况及依从性。在一项采用准实验对照组设计的多中心实地研究中,对戒烟计划的参与者在课程开始时和结束时的吸烟行为进行了询问。课程结束一年后,通过电话联系了1319名参与者。在1052名能够接受访谈的参与者中,312名受试者(29.7%)报告使用过戒烟药物,而85.2%的药物使用者更喜欢尼古丁替代疗法。客观的药物依从性为13.2%。79.3%的药物使用者认为他们坚持使用了药物。开始使用药物的参与者和未使用者之间没有显著差异(长期戒烟率:未使用药物者为34.6%,使用药物者为31.7%;p = 0.34)。提供额外的戒烟药物并不能改善现代戒烟小组计划的效果。这一发现以及药物依从性的缺乏,让人对在以强化认知行为为基础、专注于行为改变的戒烟计划之外提供戒烟药物的有效性产生怀疑。