Erkie Mengistu, Feleke Yeweyenhareg, Desalegne Fikreselam, Anbessie Jobira, Shibre Teshome
Ethiop Med J. 2013 Oct;51(4):249-59.
Depression is a major factor in causing hospital admissions and deaths in persons with diabetes mellitus. So far there is no study available on depression among Ethiopian diabetic patients.
This study aimed to determine the magnitude of clinical depression in diabetic patients and its association with the various clinical and sociodemographic factors related to diabetes mellitus.
313 diabetic patients were selected from diabetic clinics of Black Lion & St. Paul hospitals, using systematic randomized sampling technique and assessed for over a period of three months, October - December 2009. Presence and severity of depression was evaluated using clinical interviews and a structured questionnaire, the Hamilton Depression Rating Scale.
Of the total 313 patients, females account for 58.8% (n = 184), patients having type I diabetes 37.2% (n = 116) and type 2 diabetes 62.8% (n = 197). The average duration of illness with diabetes among male patients is found to be 8.2 +/- 6 years and 10.3 +/- 8 years for female patients. The mean duration of diabetes is 9.4 +/- 7.2 years. The magnitude of depression was 61% (n = 188) with mild, moderate, severe depression occurring in 40.9%, 14.7% and 4.5% of patients respectively. In this study depression diagnosed in 52.6% (n = 61) of type 1 DM and 64.8% (n = 127) of type 2 DM, 63% (n = 116) of females and 55.8% (n = 72) males. Occurrence of depression was more in patients with diabetic complications 68.2% (n = 107) and among patients in 36-54 years age group 66.7% (n = 80) compared to the rest age groups. The diagnosis of depression was also more prevalent in those with educational status below secondary level 63.9% (n = 152), (X2 = 5.868, P = 0.0075), among those with duration of DM greater than 5 yrs, 64.2% (n = 140) (X2 = 58.52, p < 0.023).
Depression is an important psychiatric co morbidity in diabetic patients. The magnitude of depression in our study is significantly higher than reports from other countries. Raising awareness about co morbid emotional disorders in such chronic illnesses and availing effective treatment for depression with the basic diabetic care at these clinics may improve glycemia and diabetic related complications.
抑郁症是导致糖尿病患者住院和死亡的主要因素。迄今为止,尚无关于埃塞俄比亚糖尿病患者抑郁症的研究。
本研究旨在确定糖尿病患者中临床抑郁症的严重程度及其与糖尿病相关的各种临床和社会人口统计学因素的关联。
采用系统随机抽样技术,从黑狮医院和圣保罗医院的糖尿病诊所选取313例糖尿病患者,并在2009年10月至12月的三个月期间进行评估。使用临床访谈和结构化问卷汉密尔顿抑郁量表评估抑郁症的存在和严重程度。
在总共313例患者中,女性占58.8%(n = 184),1型糖尿病患者占37.2%(n = 116),2型糖尿病患者占62.8%(n = 197)。男性患者患糖尿病的平均病程为8.2±6年,女性患者为10.3±8年。糖尿病的平均病程为9.4±7.2年。抑郁症的严重程度为61%(n = 188),轻度、中度和重度抑郁症分别发生在40.9%、14.7%和4.5%的患者中。在本研究中,1型糖尿病患者中有52.6%(n = 61)被诊断为抑郁症,2型糖尿病患者中有64.8%(n = 127),女性中有63%(n = 116),男性中有55.8%(n = 72)。糖尿病并发症患者中抑郁症的发生率更高,为68.2%(n = 107),36 - 54岁年龄组的患者中抑郁症的发生率为66.7%(n = 80),高于其他年龄组。抑郁症的诊断在教育程度低于中学水平的患者中也更为普遍,为63.9%(n = 152)(X2 = 5.868,P = 0.0075),在糖尿病病程大于5年的患者中为64.2%(n = 140)(X2 = 58.52,p < 0.023)。
抑郁症是糖尿病患者重要的精神共病。我们研究中抑郁症的严重程度明显高于其他国家的报告。提高对这类慢性疾病中共病情绪障碍的认识,并在这些诊所为抑郁症提供与基本糖尿病护理相结合的有效治疗,可能会改善血糖水平和糖尿病相关并发症。