Teshome Henok Mulugeta, Ayalew Getenet Dessie, Shiferaw Fasil Wagnew, Leshargie Cheru Tesema, Boneya Dube Jara
Department of Nursing, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Department of Public Health, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Depress Res Treat. 2018 May 23;2018:6135460. doi: 10.1155/2018/6135460. eCollection 2018.
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. Depression is one of the major important public health problems that is often comorbid with diabetes. Despite the huge effect of comorbid depression and diabetes, the overall pooled prevalence of depression among diabetic patients in the country level remains unknown. Therefore, the objective of this systematic review and meta-analysis is to estimate the pooled prevalence of depression among patients with diabetes mellitus in Ethiopia.
Data extraction was designed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Studies were accessed through electronic web-based search from PubMed, Cochrane Library, Google Scholar, Embase, and PsycINFO. All statistical analyses were done using STATA version 11 software using random effects model. The pooled prevalence was presented in forest plots.
A total of 9 studies with 2944 participants were included in this meta-analysis and the overall pooled estimated prevalence of depression among diabetic patients in Ethiopia was 39.73% (95% CI (28.02%, 51.45%)). According to subgroup analysis the estimated prevalence of depression in Addis Ababa was 52.9% (95% CI: 36.93%, 68.88%) and in Oromia region was 45.49% (95% CI: 41.94, 49.03%).
The analysis revealed that the overall prevalence of comorbid depression among diabetic patients in Ethiopia was high. Therefore, Ministry of Health should design multisectorial approach and context specific interventions that address this comorbid depression in this specific group as well as general population.
糖尿病是一种以高血糖为特征的慢性代谢紊乱疾病。抑郁症是经常与糖尿病合并存在的主要公共卫生问题之一。尽管合并抑郁症和糖尿病有巨大影响，但国家层面糖尿病患者中抑郁症的总体合并患病率仍不清楚。因此，本系统评价和荟萃分析的目的是估计埃塞俄比亚糖尿病患者中抑郁症的合并患病率。
数据提取按照系统评价和荟萃分析的首选报告项目（PRISMA）指南进行设计。通过基于网络的电子搜索从PubMed、Cochrane图书馆、谷歌学术、Embase和PsycINFO获取研究。所有统计分析使用STATA 11版软件采用随机效应模型进行。合并患病率在森林图中呈现。
本荟萃分析共纳入9项研究，2944名参与者，埃塞俄比亚糖尿病患者中抑郁症的总体合并估计患病率为39.73%（95%可信区间（28.02%，51.45%））。根据亚组分析，亚的斯亚贝巴抑郁症的估计患病率为52.9%（95%可信区间：36.93%，68.88%），奥罗米亚地区为45.49%（95%可信区间：41.94，49.03%）。
分析显示埃塞俄比亚糖尿病患者中合并抑郁症的总体患病率较高。因此，卫生部应设计多部门方法和针对具体情况的干预措施，以解决这一特定群体以及普通人群中的这种合并抑郁症问题。
