Protrka Nives, Katunarić Marina, Filipović Irina, Verzak Zeljko
Acta Clin Croat. 2013 Dec;52(4):436-43.
The aim of the study was to determine the prevalence of caries in patients who are heroin addicts and the effects of salivary flow and saliva pH on its prevalence. The study included 200 subjects (100 subjects diagnosed with heroin addiction as the test group and 100 subjects taking no addictive substances as the control group). In both groups, saliva status was established by determining flow rates and pH of stimulated and unstimulated saliva. The total number of dental caries cases was determined using the DMFT index and their more specific detection in the context of localization on the tooth using the DMFS index. The DMFT index was higher in the test group (mean 18.78) than in the control group (mean 5.32), with a statistically significant difference (P < 0.000). The highest caries prevalence in both groups was recorded on occlusal dental surfaces (44.70% in the test group and 16.20% in the control group). The prevalence of caries of vestibular dental surfaces was higher in the test group (9.40%) than in the control group (2.34%), and the difference was statistically significant (P < 0.000). A statistically significant correlation was established between heroin addiction and reduced production of unstimulated saliva (P < 0.001) and stimulated saliva (P < 0.002), as well as pH values of stimulated saliva (P < 0.001) and unstimulated saliva (P < 0.001). In conclusion, a higher prevalence of caries of hard dental tissue was found in the test group. The flow of stimulated and unstimulated saliva as was as saliva pH was lower in the test group.
该研究的目的是确定海洛因成瘾患者的龋齿患病率以及唾液流量和唾液pH值对其患病率的影响。该研究纳入了200名受试者(100名被诊断为海洛因成瘾的受试者作为试验组,100名未服用成瘾物质的受试者作为对照组)。在两组中,通过测定刺激唾液和未刺激唾液的流速和pH值来确定唾液状态。使用DMFT指数确定龋齿病例总数,并使用DMFS指数在牙齿定位的背景下进行更具体的检测。试验组的DMFT指数(平均18.78)高于对照组(平均5.32),差异具有统计学意义(P<0.000)。两组中龋齿患病率最高的均为牙合面(试验组为44.70%,对照组为16.20%)。试验组前庭牙面的龋齿患病率(9.40%)高于对照组(2.34%),差异具有统计学意义(P<0.000)。海洛因成瘾与未刺激唾液分泌减少(P<0.001)、刺激唾液分泌减少(P<0.002)以及刺激唾液pH值(P<0.001)和未刺激唾液pH值(P<0.001)之间存在统计学意义的相关性。总之,试验组硬牙组织的龋齿患病率更高。试验组中刺激唾液和未刺激唾液的流量以及唾液pH值均较低。