Kes Vanja Basić, Cesarik Marijan, Matovina Lucija Zadro, Zavoreo Iris, Corić Lejla, Drnasin Sara, Demarin Vida
Acta Clin Croat. 2013 Dec;52(4):464-71.
The National Center for Complementary and Alternative Medicine defines complementary and alternative medicine as a group of diverse medical and health care systems, practices and products that are not generally considered part of conventional medicine. Multiple sclerosis (MS) is a chronic disabling disease of the central nervous system that affects people during early adulthood. In spite of many approved medications, the treatment options in MS are limited. Many people with MS explore complementary and alternative medicine (CAM) treatments to help control their MS and treat their symptoms. Surveys suggest that up to 70% of people with MS have tried one or more CAM treatment for their MS. People with MS using CAM generally report deriving some benefit from therapies. The CAM therapies most frequently used include diet, omega-3 fatty acids and antioxidants. The therapies with highest potential among CAM therapies that warrant further investigation are low-fat diet, omega-3 fatty acids, lipoic acid, and vitamin D supplementation as potential anti-inflammatory and neuroprotective agents in both relapsing and progressive forms of MS. There are very limited researches evaluating the safety and efficacy of CAM in MS. However, in recent years, the USA National Institutes of Health and the National Multiple Sclerosis Society have been actively supporting the researches in this very important area.
美国国立补充与替代医学中心将补充与替代医学定义为一组不同的医疗保健系统、实践和产品，这些通常不被视为传统医学的一部分。多发性硬化症（MS）是一种影响成年早期人群的中枢神经系统慢性致残疾病。尽管有许多已获批的药物，但MS的治疗选择仍然有限。许多MS患者探索补充与替代医学（CAM）疗法来帮助控制病情并治疗症状。调查显示，高达70%的MS患者尝试过一种或多种CAM疗法来治疗他们的MS。使用CAM的MS患者普遍报告称从这些疗法中获得了一些益处。最常使用的CAM疗法包括饮食、ω-3脂肪酸和抗氧化剂。在CAM疗法中，最有潜力值得进一步研究的疗法是低脂饮食、ω-3脂肪酸、硫辛酸以及补充维生素D，它们在复发型和进展型MS中均作为潜在的抗炎和神经保护剂。评估CAM在MS中的安全性和有效性的研究非常有限。然而，近年来，美国国立卫生研究院和美国国家多发性硬化症协会一直在积极支持这一非常重要领域的研究。
