Apel Annett, Greim Brigitte, Zettl Uwe K
University of Rostock, Department of Neurology, Gehlsheimer Str. 20, 18147 Rostock, Germany.
Complement Ther Med. 2005 Dec;13(4):258-63. doi: 10.1016/j.ctim.2005.05.006. Epub 2005 Aug 31.
The purpose of the study was to examine the prevalence and characteristics of the utilisation of complementary and alternative medicine (CAM) by patients with multiple sclerosis (MS).
Cross-sectional study using a semi-structured interview.
One hundred and fifty-four MS patients were examined by interview to collect sociodemographic and disease-related variables as well as aspects of their usage of CAM. The investigation was completed by data from neurological examination.
Reported utilisation of CAM by MS patients.
At the time of the investigation 61.7% (n = 95) of the MS patients reported that they were currently using CAM. Most of the therapies utilised (90.3%; n = 205) were complementary and only 9.7% (n = 22) were alternative choices. Users of complementary medicine were more severely affected by the disease than non-users, but no sociodemographic differences between users and non-users were found. Concerning the efficacy of CAM, 65.8% (n = 146) of MS patients reported improvement, 32.9% (n = 73) no influence, and 1.3% (n = 3) worsening of their condition. 4.5% (n = 10) of the CAM therapies were accompanied by slight side-effects.
A large proportion of MS patients use unconventional treatments, yet clinical studies on the efficacy of CAM in these cases have not been undertaken. Therefore, further research on their motivation and on objective effects of CAM is required.
本研究旨在调查多发性硬化症(MS)患者使用补充和替代医学(CAM)的患病率及特征。
采用半结构化访谈的横断面研究。
通过访谈对154例MS患者进行调查,以收集社会人口统计学和疾病相关变量以及他们使用CAM的情况。通过神经学检查数据完成调查。
MS患者报告的CAM使用情况。
在调查时,61.7%(n = 95)的MS患者报告他们目前正在使用CAM。所使用的大多数疗法(90.3%;n = 205)是补充性的,只有9.7%(n = 22)是替代性选择。使用补充医学的患者比未使用者受疾病影响更严重,但未发现使用者和未使用者之间存在社会人口统计学差异。关于CAM的疗效,65.8%(n = 146)的MS患者报告病情有所改善,32.9%(n = 73)报告无影响,1.3%(n = 3)报告病情恶化。4.5%(n = 10)的CAM疗法伴有轻微副作用。
很大一部分MS患者使用非常规治疗方法,但尚未对CAM在这些病例中的疗效进行临床研究。因此,需要进一步研究他们使用CAM的动机以及CAM的客观效果。