Brown Emma S, Allsopp Philip J, Magee Pamela J, Gill Chris I R, Nitecki Sonja, Strain Conall R, McSorley Emeir M
Nutr Rev. 2014 Mar;72(3):205-16. doi: 10.1111/nure.12091.
Seaweeds may have an important role in modulating chronic disease. Rich in unique bioactive compounds not present in terrestrial food sources, including different proteins (lectins, phycobiliproteins, peptides, and amino acids), polyphenols, and polysaccharides, seaweeds are a novel source of compounds with potential to be exploited in human health applications. Purported benefits include antiviral, anticancer, and anticoagulant properties as well as the ability to modulate gut health and risk factors for obesity and diabetes. Though the majority of studies have been performed in cell and animal models, there is evidence of the beneficial effect of seaweed and seaweed components on markers of human health and disease status. This review is the first to critically evaluate these human studies, aiming to draw attention to gaps in current knowledge, which will aid the planning and implementation of future studies.
海藻可能在调节慢性病方面发挥重要作用。海藻富含陆地食物来源中不存在的独特生物活性化合物,包括不同的蛋白质(凝集素、藻胆蛋白、肽和氨基酸)、多酚和多糖,是具有在人类健康应用中被开发潜力的新型化合物来源。据称其益处包括抗病毒、抗癌和抗凝血特性,以及调节肠道健康和肥胖及糖尿病风险因素的能力。尽管大多数研究是在细胞和动物模型中进行的,但有证据表明海藻及其成分对人类健康和疾病状态标志物有有益影响。本综述首次对这些人体研究进行批判性评估,旨在提请关注当前知识中的空白,这将有助于未来研究的规划和实施。