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巴西卡车司机的行程长度与药物使用之间的关联。

Association between travel length and drug use among Brazilian truck drivers.

作者信息

Sinagawa Daniele Mayumi, De Carvalho Heráclito Barbosa, Andreuccetti Gabriel, Do Prado Natanael Vitoriano, De Oliveira Keziah Cristina Barbosa Gruber, Yonamine Mauricio, Muñoz Daniel Romero, Gjerde Hallvard, Leyton Vilma

机构信息

a Faculty of Medicine, University of Sao Paulo , Sao Paulo , Brazil.

出版信息

Traffic Inj Prev. 2015;16(1):5-9. doi: 10.1080/15389588.2014.906589. Epub 2014 Sep 26.

Abstract

OBJECTIVE

To investigate whether the use of the stimulants amphetamines and cocaine by truck drivers in Brazil was related to travel length.

METHODS

Truck drivers were randomly stopped by the Federal Highway Police on interstate roads in Sao Paulo State during morning hours from 2008 to 2011 and invited to participate in the project "Comandos de Saúde nas Rodovias" (Health Commands on the Roads). Participants were asked about the use of drugs, travel distance, and age, and gender was recorded. Samples of urine were collected and analyzed for amphetamine, benzoylecgonine (a metabolite of cocaine), and carboxytetrahydrocannabinol (THC-COOH; a metabolite of cannabis) by immunological screening and quantification by gas chromatography-mass spectroscopy.

RESULTS

Current use of amphetamine, cocaine, and cannabis was reported by 5.7%, 0.7%, and 0.3% of the truck drivers, respectively. Amphetamine, benzoylecgonine, and THC-COOH were found in urine samples from 5.4%, 2.6,% and in 1.0% of the drivers, respectively. There was a significant association between the positive cases for amphetamine and reported travel length; 9.9% of urine samples from drivers who reported travel length of more than 270 km were positive for amphetamine, and 10.9% of those drivers reported current use of amphetamines. In most cases, appetite suppressants containing amphetamines had been used, but the purpose was most often to stay awake and alert while driving. Truck drivers with travel length of more than 270 km had significantly higher odds ratio (OR) for having a urine sample that was positive for amphetamine when adjusted for age as confounding factor (OR = 9.41, 95% confidence interval [CI], 3.97-22.26). No significant association was found between the use of cocaine or cannabis and travel length.

CONCLUSION

Truck drivers who reported driving more than 270 km had significantly higher frequencies of urine samples positive for amphetamine and reported significantly more frequent current use of amphetamines than those who reported shorter driving distances.

摘要

目的

调查巴西卡车司机使用苯丙胺和可卡因等兴奋剂是否与行驶里程有关。

方法

2008年至2011年期间,联邦公路警察在圣保罗州的州际公路上于上午时段随机拦下卡车司机,并邀请他们参与“道路健康指挥部”项目。询问参与者关于药物使用、行驶距离和年龄的情况,并记录性别。收集尿液样本,通过免疫筛查分析其中的苯丙胺、苯甲酰爱康宁(可卡因的一种代谢物)和羧基四氢大麻酚(THC-COOH;大麻的一种代谢物),并通过气相色谱-质谱法定量。

结果

分别有5.7%、0.7%和0.3%的卡车司机报告当前使用苯丙胺、可卡因和大麻。在分别5.4%、2.6%和1.0%的司机尿液样本中发现了苯丙胺、苯甲酰爱康宁和THC-COOH。苯丙胺阳性病例与报告的行驶里程之间存在显著关联;报告行驶里程超过270公里的司机中,9.9%的尿液样本苯丙胺呈阳性,且10.9%的此类司机报告当前使用苯丙胺。在大多数情况下,使用的是含苯丙胺的食欲抑制剂,但目的大多是在驾驶时保持清醒和警觉。将年龄作为混杂因素进行调整后,行驶里程超过270公里的卡车司机尿液样本苯丙胺呈阳性的优势比(OR)显著更高(OR = 9.41,95%置信区间[CI],3.97 - 22.26)。未发现使用可卡因或大麻与行驶里程之间存在显著关联。

结论

报告驾驶里程超过270公里的卡车司机尿液样本苯丙胺呈阳性的频率显著高于报告较短驾驶距离的司机,且报告当前使用苯丙胺的频率也显著更高。

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