Ouellet Georges, Bouchard Josée, Ghannoum Marc, Decker Brian Scott
Division of Nephrology, Hôpital Maisonneuve-Rosemont, University of Montreal, Montreal, Quebec, Canada.
Semin Dial. 2014 Jul-Aug;27(4):342-9. doi: 10.1111/sdi.12238. Epub 2014 Apr 3.
Poisoning is a significant public health problem. In severe cases, extracorporeal treatments (ECTRs) may be required to prevent or reverse major toxicity. Available ECTRs include intermittent hemodialysis, sustained low-efficiency dialysis, intermittent hemofiltration and hemodiafiltration, continuous renal replacement therapy, hemoperfusion, therapeutic plasma exchange, exchange transfusion, peritoneal dialysis, albumin dialysis, cerebrospinal fluid exchange, and extracorporeal life support. The aim of this article was to provide an overview of the technical aspects, as well as the potential indications and limitations of the different ECTRs used for poisoned patients.
中毒是一个重大的公共卫生问题。在严重情况下，可能需要进行体外治疗（ECTR）以预防或逆转严重毒性。可用的ECTR包括间歇性血液透析、持续性低效透析、间歇性血液滤过和血液透析滤过、连续性肾脏替代治疗、血液灌流、治疗性血浆置换、换血疗法、腹膜透析、白蛋白透析、脑脊液置换以及体外生命支持。本文旨在概述用于中毒患者的不同ECTR的技术方面以及潜在的适应症和局限性。
