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UH series of monoclonal antibodies recognizing major histocompatibility complex class II antigen(s) of Japanese monkeys (Macaca fuscata).

作者信息

Murayama Y, Ishida T, Hashiba K, Noguchi A, Takenaka O

机构信息

Primate Research Institute, Kyoto University, Aichi, Japan.

出版信息

J Med Primatol. 1989;18(2):111-23.

PMID:2469798
Abstract

Six mouse monoclonal antibodies were developed by immunization with a Japanese monkey cell line. These monoclonal antibodies, designated the UH series, reacted with large populations of peripheral B cells and monocytes, but not with T cells. The distribution of reactivities and the molecular weight of the membrane antigens recognized were similar to those of the HLA-DR monoclonal antibody; one inhibited the binding of HLA-DR. Human interferon-gamma induced increased expressions of all the UH antigen epitopes.

摘要

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