Staessen J, Fagard R, Van Hoof R, Amery A
Hypertension and Cardiovascular Rehabilitation Unit, Department of Pathophysiology, K.U. Leuven, Belgium.
J Cardiovasc Pharmacol. 1988;12 Suppl 8:S33-9.
The different intervention trials in elderly hypertensive subjects are compatible with the hypothesis that antihypertensive drug treatment decreases cardiovascular mortality, mainly by a reduction of cerebrovascular mortality. Antihypertensive drug treatment in elderly hypertensive subjects also leads to a decrease in fatal and nonfatal cardiovascular and cerebrovascular events. It has not yet been proven whether antihypertensive drug treatment should be recommended for symptomless patients with isolated systolic hypertension and for patients with uncomplicated hypertension above the age of 80 years.
降压药物治疗主要通过降低脑血管死亡率来降低心血管死亡率。老年高血压患者的降压药物治疗还可导致致命和非致命的心血管及脑血管事件减少。对于单纯收缩期高血压无症状患者以及80岁以上无并发症高血压患者，是否应推荐进行降压药物治疗尚未得到证实。
