CDKN1A：脂肪肝中的一把双刃剑？ - Suppr

CDKN1A: a double-edged sword in fatty liver?

作者信息

Valenti Luca, Dongiovanni Paola

机构信息

Department of Pathophysiology and Transplantation; Università degli Studi di Milano; Milan, Italy; Internal Medicine; Fondazione IRCCS Ca' Granda Ospedale Policlinico Milano; Milan, Italy.

Internal Medicine; Fondazione IRCCS Ca' Granda Ospedale Policlinico Milano; Milan, Italy.

出版信息

Cell Cycle. 2014;13(9):1371-2. doi: 10.4161/cc.28754. Epub 2014 Apr 3.

DOI:10.4161/cc.28754

PMID:24699009

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4050133/

Abstract

摘要

相似文献

CDKN1A: a double-edged sword in fatty liver?

Cell Cycle. 2014;13(9):1371-2. doi: 10.4161/cc.28754. Epub 2014 Apr 3.

Gene polymorphisms of cellular senescence marker p21 and disease progression in non-alcohol-related fatty liver disease.

Cell Cycle. 2014;13(9):1489-94. doi: 10.4161/cc.28471. Epub 2014 Mar 11.

The anti-aging promise of p21.

Cell Cycle. 2017;16(21):1997-1998. doi: 10.1080/15384101.2017.1377500. Epub 2017 Sep 29.

Hepatocyte expression of the senescence marker p21 is linked to fibrosis and an adverse liver-related outcome in alcohol-related liver disease.

PLoS One. 2013 Sep 23;8(9):e72904. doi: 10.1371/journal.pone.0072904. eCollection 2013.

Lipotoxic effect of p21 on free fatty acid-induced steatosis in L02 cells.

PLoS One. 2014 Apr 30;9(4):e96124. doi: 10.1371/journal.pone.0096124. eCollection 2014.

Cellular senescence in liver diseases: From mechanisms to therapies.

Int Immunopharmacol. 2023 Aug;121:110522. doi: 10.1016/j.intimp.2023.110522. Epub 2023 Jun 27.

IGF-I induces senescence of hepatic stellate cells and limits fibrosis in a p53-dependent manner.

Sci Rep. 2016 Oct 10;6:34605. doi: 10.1038/srep34605.

Soluble egg antigens of Schistosoma japonicum induce senescence in activated hepatic stellate cells by activation of the STAT3/p53/p21 pathway.

Sci Rep. 2016 Aug 4;6:30957. doi: 10.1038/srep30957.

CDK4/6-inhibiting drug substitutes for p21 and p16 in senescence: duration of cell cycle arrest and MTOR activity determine geroconversion.

Cell Cycle. 2013 Sep 15;12(18):3063-9. doi: 10.4161/cc.26130. Epub 2013 Aug 22.

Promotion of cellular senescence by THG-1/TSC22D4 knockout through activation of JUNB.

Biochem Biophys Res Commun. 2020 Feb 19;522(4):897-902. doi: 10.1016/j.bbrc.2019.11.145. Epub 2019 Dec 3.

引用本文的文献

Aging Dis. 2021 Aug 1;12(5):1238-1251. doi: 10.14336/AD.2020.1227. eCollection 2021 Aug.

Elimination of Age-Associated Hepatic Steatosis and Correction of Aging Phenotype by Inhibition of cdk4-C/EBPα-p300 Axis.

Cell Rep. 2018 Aug 7;24(6):1597-1609. doi: 10.1016/j.celrep.2018.07.014.

Telomeres, NAFLD and Chronic Liver Disease.

Int J Mol Sci. 2016 Mar 15;17(3):383. doi: 10.3390/ijms17030383.

Modulation of insulin degrading enzyme activity and liver cell proliferation.

Cell Cycle. 2015;14(14):2293-300. doi: 10.1080/15384101.2015.1046647. Epub 2015 May 6.

Cross-species toxicogenomic analyses and phenotypic anchoring in response to groundwater low-level pollution.

BMC Genomics. 2014 Dec 5;15(1):1067. doi: 10.1186/1471-2164-15-1067.

本文引用的文献

Gene polymorphisms of cellular senescence marker p21 and disease progression in non-alcohol-related fatty liver disease.

Cell Cycle. 2014;13(9):1489-94. doi: 10.4161/cc.28471. Epub 2014 Mar 11.

Genetic predisposition in NAFLD and NASH: impact on severity of liver disease and response to treatment.

Curr Pharm Des. 2013;19(29):5219-38. doi: 10.2174/13816128113199990381.

Hepatocyte senescence predicts progression in non-alcohol-related fatty liver disease.

J Hepatol. 2013 Mar;58(3):549-56. doi: 10.1016/j.jhep.2012.10.031. Epub 2012 Nov 8.

Liver transplantation for hepatocellular carcinoma in a patient with a novel telomerase mutation and steatosis.

J Hepatol. 2013 Feb;58(2):399-401. doi: 10.1016/j.jhep.2012.09.011. Epub 2012 Sep 19.

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease.

Hepatology. 2010 Apr;51(4):1209-17. doi: 10.1002/hep.23622.

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease.

Nat Genet. 2008 Dec;40(12):1461-5. doi: 10.1038/ng.257. Epub 2008 Sep 25.

From fat to inflammation.

Gastroenterology. 2006 Jan;130(1):207-10. doi: 10.1053/j.gastro.2005.11.017.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

CDKN1A: a double-edged sword in fatty liver?

作者信息

机构信息

出版信息

相似文献

引用本文的文献

本文引用的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献

本文引用的文献