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原发性肝癌肝部分切除术的评估

Evaluation of partial hepatectomy for primary liver carcinoma.

作者信息

Li G H, Zhu S L, Li J Q, Zhan Y Q

机构信息

Department of Abdominal Surgery, Tumor Hospital of Sun Yat-Sen University of Medical Sciences, Guangzhou, People's Republic of China.

出版信息

J Surg Oncol. 1989 May;41(1):5-8. doi: 10.1002/jso.2930410105.

Abstract

From 1964 to 1985, 120 cases of primary liver carcinoma had undergone hepatectomy in our hospital. Seven of these cases underwent hepatic lobectomy, 28 cases had palliative hepatic resection, and 85 cases had partial hepatectomy. We introduced different surgical modes and compared the mortality, survival rates, and complications between the hepatic lobectomy and partial hepatectomy groups. The mortality rates of these two groups were 14.3 and 3.5%, respectively, and the 1, 3, and 5 year survival rates were 83.3, 33.3, and 16.7 and 68.8, 48.1, and 20%, respectively. In the palliative hepatectomy group (28 cases), ten cases received combined radiotherapy postoperation. Most of these cases died during the first year postoperation. Primary liver cancer in Asia is commonly associated with hepatic cirrhosis. We suggest that partial hepatectomy is suitable for such patients. The results of the present series showed that the outcomes of the hepatic lobectomy and partial hepatectomy groups did not differ, but in partial hepatectomy, the operative mortality and complications were reduced, bleeding minimized, and operation time also shortened.

摘要

1964年至1985年,我院对120例原发性肝癌患者实施了肝切除术。其中7例行肝叶切除术,28例行姑息性肝切除术,85例行肝部分切除术。我们采用了不同的手术方式,并比较了肝叶切除术组和肝部分切除术组之间的死亡率、生存率及并发症情况。这两组的死亡率分别为14.3%和3.5%,1年、3年和5年生存率分别为83.3%、33.3%、16.7%以及68.8%、48.1%、20%。在姑息性肝切除术组(28例)中,10例患者术后接受了联合放疗。这些患者大多在术后第一年死亡。亚洲的原发性肝癌通常与肝硬化相关。我们认为肝部分切除术适用于此类患者。本系列研究结果显示,肝叶切除术组和肝部分切除术组的疗效无差异,但肝部分切除术可降低手术死亡率和并发症发生率,减少出血,缩短手术时间。

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