Pommier R F, Woltering E A, Campbell J R, Fletcher W S
Am J Surg. 1987 May;153(5):428-33. doi: 10.1016/0002-9610(87)90784-7.
Fifty consecutive major hepatic resections were performed for primary and secondary malignant neoplasms of the liver. There were 7 children and 9 adults with primary neoplasms and 34 patients with secondary neoplasms. The mortality rate was 0 percent and the morbidity rate, 14 percent. Postoperative morbidity correlated with operative blood loss. The 5 year survival rates for children and adults with primary neoplasms were 42 percent and 22 percent, respectively, and the 5 year survival rate for adults with secondary neoplasms was 15 percent. Factors such as disease-free interval, number of metastases, and stage of metastases did not influence the postoperative survival rate. Also, there was no difference in survival rate between patients whose metastases were resected by lobectomy or segmentectomy and those whose metastases were resected by wedge resection.
对50例因原发性和继发性肝脏恶性肿瘤而进行的连续性大肝切除术进行了研究。其中7例儿童和9例成人患有原发性肿瘤,34例患者患有继发性肿瘤。死亡率为0%,发病率为14%。术后发病率与术中失血量相关。患有原发性肿瘤的儿童和成人的5年生存率分别为42%和22%,患有继发性肿瘤的成人的5年生存率为15%。无病间期、转移灶数量和转移分期等因素不影响术后生存率。此外,通过肝叶切除术或肝段切除术切除转移灶的患者与通过楔形切除术切除转移灶的患者之间的生存率没有差异。