电子传递的抑制强烈影响拟南芥线粒体中的转录和转录本水平。
Inhibition of the electron transport strongly affects transcription and transcript levels in Arabidopsis mitochondria.
作者信息
Zubo Yan O, Potapova Tatyana V, Yamburenko Maria V, Tarasenko Vladislav I, Konstantinov Yuri M, Börner Thomas
机构信息
Institute of Biology-Genetics, Humboldt University, Chaussestr. 117, 10115 Berlin, Germany.
Institute of Biology-Genetics, Humboldt University, Chaussestr. 117, 10115 Berlin, Germany; The Siberian Institute of Plant Physiology and Biochemistry SB RAS, Lermontova St., 132, Irkutsk 664033, Russia.
出版信息
Mitochondrion. 2014 Nov;19 Pt B:222-30. doi: 10.1016/j.mito.2014.03.011. Epub 2014 Mar 31.
Mitochondrial transcription rate and RNA steady-state levels were examined in shoots of Arabidopsis seedlings. The shoots were treated with inhibitors of complex III and IV of the cytochrome pathway (CP) and with an inhibitor of the alternative oxidase (AOX) of the mitochondrial electron transport chain. The inhibition of AOX and CP complexes III and IV affected transcription and transcript levels in different ways. CP and AOX inhibitors had opposite effects. Our data support the idea that the redox state of the electron transport chain is involved in the regulation of mitochondrial gene expression at transcriptional and post-transcriptional levels.
在拟南芥幼苗的茎中检测了线粒体转录速率和RNA稳态水平。用细胞色素途径（CP）的复合物III和IV的抑制剂以及线粒体电子传递链的交替氧化酶（AOX）的抑制剂处理茎。AOX以及CP复合物III和IV的抑制以不同方式影响转录和转录本水平。CP和AOX抑制剂具有相反的作用。我们的数据支持电子传递链的氧化还原状态参与线粒体基因表达在转录和转录后水平调控的观点。
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