造血细胞中细胞分裂、分化定向和成熟的分子调控。
The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells.
作者信息
Metcalf D
机构信息
Cancer Research Unit, Walter and Eliza Hall Institute, Royal Melbourne Hospital, Victoria, Australia.
出版信息
Nature. 1989 May 4;339(6219):27-30. doi: 10.1038/339027a0.
DOI:10.1038/339027a0
PMID:2469962
Abstract
Several glycoproteins that control blood-cell production and function have been purified and sequenced. The four colony-stimulating factors interact in a complex way to regulate the differentiation and maturation of the granulocyte and macrophage lineages and have potential applications for the clinical manipulation of blood-cell production.
摘要
几种控制血细胞生成和功能的糖蛋白已被纯化和测序。这四种集落刺激因子以复杂的方式相互作用，以调节粒细胞和巨噬细胞谱系的分化和成熟，并在临床操控血细胞生成方面具有潜在应用。
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