Praud J P, Carofilis A, Bridey F, Lacaille F, Dehan M, Gaultier C L
Laboratory of Physiology, CNRS UA 1159, Hospital Antoine Béclère, Clamart, France.
Pediatr Pulmonol. 1989;6(3):180-2. doi: 10.1002/ppul.1950060310.
In 60 neonates (gestational age, 26.5-40 weeks; postnatal age, 1-14 days) and in 11 infants (gestational age, 26-33 weeks; postnatal age, 4.5-38 weeks), the accuracy of two wavelength pulse oximetry was examined. A total of 112 comparisons between transcutaneous pulse oximetry saturation (StcO2, NELLCOR N-100) and arterial oxygen saturation (SaO2, OSM2 RADIOMETER) were obtained. SaO2 ranged from 80 to 100%. Criteria for comparison between StcO2 and SaO2 were standardized: patients in behavioral state 1, StcO2 stable for 2 min, and arterial samples drawn from an indwelling arterial line. StcO2 was significantly related to SaO2 (P less than 0.01), but the difference, StcO2 - SaO2, significantly increased when SaO2 decreased [StcO2 - SaO2(%) = -0.39 SaO2(%) + 37.95; r = -0.64, P less than 0.01]. No significant relationship was found between StcO2 - SaO2 and either bilirubinemia (range, 5-222 mumol/L) or fetal hemoglobin (HbF) (range, 12-95%). We conclude that StcO2 overestimates SaO2 when SaO2 decreases, and this overestimation is not due to high levels of bilirubin or HbF.
对60例新生儿（胎龄26.5 - 40周；出生后年龄1 - 14天）和11例婴儿（胎龄26 - 33周；出生后年龄4.5 - 38周）进行了双波长脉搏血氧饱和度测定的准确性研究。共获得112次经皮脉搏血氧饱和度（StcO2，Nellcor N - 100）与动脉血氧饱和度（SaO2，OSM2 Radiometer）的对比数据。SaO2范围为80%至100%。StcO2与SaO2对比的标准进行了统一：行为状态为1的患者，StcO2稳定2分钟，且动脉样本取自留置动脉导管。StcO2与SaO2显著相关（P < 0.01），但当SaO2降低时，两者差值StcO2 - SaO2显著增大[StcO2 - SaO2(%) = -0.39 SaO2(%) + 37.95；r = -0.64，P < 0.01]。未发现StcO2 - SaO2与胆红素血症（范围5 - 222 μmol/L）或胎儿血红蛋白（HbF）（范围12 - 95%）之间存在显著关系。我们得出结论，当SaO2降低时，StcO2会高估SaO2，且这种高估并非由高胆红素水平或HbF所致。
