University Centre for Nursing and Midwifery, Department of Public Health Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Res Nurs Health. 2014 Jun;37(3):204-18. doi: 10.1002/nur.21593. Epub 2014 Apr 3.
The aim of this analysis was to identify the association between incontinence-associated dermatitis (IAD), its most important etiologic factors (incontinence and moisture), and pressure ulcers (PUs). A systematic review and meta-analysis were performed. We searched Medline, Embase, CINAHL, Web of Science, and the Cochrane Library for relevant papers dating through March 15, 2013. Fifty-eight studies were included. Measures of relative effect at the univariate level were meta-analyzed. In most studies (86%), a significant association between variables of interest was found, with pooled odds ratios of PUs in univariate models between 1.92 (95% CI 1.54-2.38) for urinary incontinence and 4.99 (95% CI 2.62-9.50) for double incontinence (p < .05). This evidence indicates an association between IAD, its most important etiological factors, and PUs. Methodological issues should be considered when interpreting the results of this review.
本分析旨在确定失禁相关性皮炎（IAD）与其最重要的病因（失禁和潮湿）以及压力性溃疡（PU）之间的关联。进行了系统评价和荟萃分析。我们检索了 Medline、Embase、CINAHL、Web of Science 和 Cochrane 图书馆中截至 2013 年 3 月 15 日的相关文献。共纳入 58 项研究。在单变量水平上对相对效应的衡量指标进行了荟萃分析。在大多数研究（86%）中，发现感兴趣变量之间存在显著关联，在单变量模型中，尿失禁的 PU 比值比为 1.92（95%CI 1.54-2.38），双重失禁为 4.99（95%CI 2.62-9.50）（p<0.05）。这一证据表明 IAD 与其最重要的病因之间存在关联，以及 IAD 与 PU 之间存在关联。在解释本综述的结果时，应考虑方法学问题。
