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勒米尔综合征:一种常被漏诊的危及生命的感染。

Lemierre's syndrome: An often missed life-threatening infection.

作者信息

Srivali Narat, Ungprasert Patompong, Kittanamongkolchai Wonngarm, Ammannagari Nischala

机构信息

Department of Internal Medicine, Bassett Medical Center and Columbia University College of Physicians and Surgeons, Cooperstown, New York 13326, USA.

出版信息

Indian J Crit Care Med. 2014 Mar;18(3):170-2. doi: 10.4103/0972-5229.128708.

DOI:10.4103/0972-5229.128708
PMID:24701068
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3963201/
Abstract

Lemierre's syndrome is an uncommon, but fatal infection of the internal jugular vein (IJV) that is usually caused by Fusobacteirum necrophorum although a wide range of bacteria has been reported as causative agents. Typical symptoms include fever, sore throat, neck swelling, pulmonary symptoms and arthralgia; however, the diagnosis of this infection is frequently overlooked as initial manifestation might be subtle and non-specific. Definite diagnosis requires positive blood culture and radiological evidence of thrombus in the IJV. We describe a case of a patient with Lemierre's syndrome who was initially misdiagnosed with viral upper respiratory tract infection. High index of suspicion is pivotal to the diagnosis of this infection and Lemierre's syndrome should always be considered as a potential cause of sepsis in an otherwise healthy patient.

摘要

勒米尔综合征是一种罕见但致命的颈内静脉感染,通常由坏死梭杆菌引起,尽管已有多种细菌被报道为病原体。典型症状包括发热、咽痛、颈部肿胀、肺部症状和关节痛;然而,这种感染的诊断常常被忽视,因为其初始表现可能不明显且不具特异性。明确诊断需要血培养阳性以及颈内静脉血栓形成的影像学证据。我们描述了一例最初被误诊为病毒性上呼吸道感染的勒米尔综合征患者。高度怀疑对于这种感染的诊断至关重要,对于原本健康的患者出现败血症时,应始终将勒米尔综合征视为潜在病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a101/3963201/c5aea8d9a470/IJCCM-18-170-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a101/3963201/c5aea8d9a470/IJCCM-18-170-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a101/3963201/c5aea8d9a470/IJCCM-18-170-g001.jpg

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本文引用的文献

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Lemierre's syndrome due to Fusobacterium necrophorum.坏死梭杆菌引起的李-孟二氏综合征。
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