• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

参与人类精液凝胶化和液化过程的前列腺和精囊分泌蛋白的结构与功能

Structure and function of prostatic- and seminal vesicle-secreted proteins involved in the gelation and liquefaction of human semen.

作者信息

Lilja H

机构信息

Department of Clinical Chemistry, University of Lund, Malmö General Hospital, Sweden.

出版信息

Scand J Clin Lab Invest Suppl. 1988;191:13-20.

PMID:2470129
Abstract

At ejaculation, the epididymal spermatozoa mix with the secretions produced by the seminal vesicles and the prostate. The glandular secretions immediately turns into a gel-like structure which entraps the spermatozoa. The ejaculated spermatozoa become progressively motile as the gel dissolves. The discovery, structure, and interactions of proteins involved in these post-ejaculatory phase reactions of semen are here reported.

摘要

在射精时,附睾精子与精囊和前列腺产生的分泌物混合。腺体分泌物立即变成一种凝胶状结构,将精子困住。随着凝胶溶解,射出的精子逐渐具有运动能力。本文报道了精液射精后阶段反应中涉及的蛋白质的发现、结构和相互作用。

相似文献

1
Structure and function of prostatic- and seminal vesicle-secreted proteins involved in the gelation and liquefaction of human semen.参与人类精液凝胶化和液化过程的前列腺和精囊分泌蛋白的结构与功能
Scand J Clin Lab Invest Suppl. 1988;191:13-20.
2
Seminal vesicle-secreted proteins and their reactions during gelation and liquefaction of human semen.精囊分泌蛋白及其在人类精液凝胶化和液化过程中的反应。
J Clin Invest. 1987 Aug;80(2):281-5. doi: 10.1172/JCI113070.
3
Characterization of prostate-specific antigen proteolytic activity on its major physiological substrate, the sperm motility inhibitor precursor/semenogelin I.前列腺特异性抗原对其主要生理底物——精子活力抑制因子前体/精液凝胶蛋白I的蛋白水解活性的表征
Biochemistry. 1997 Apr 1;36(13):3811-9. doi: 10.1021/bi9626158.
4
Distribution and tissue expression of semenogelin I and II in man as demonstrated by in situ hybridization and immunocytochemistry.通过原位杂交和免疫细胞化学法显示的人精浆蛋白I和II的分布及组织表达
J Androl. 1996 Jan-Feb;17(1):17-26.
5
The GPI-anchored CD52 antigen of the sperm surface interacts with semenogelin and participates in clot formation and liquefaction of human semen.精子表面的糖基磷脂酰肌醇(GPI)锚定的CD52抗原与精液凝胶蛋白相互作用,并参与人类精液的凝块形成和液化过程。
Mol Reprod Dev. 2008 Feb;75(2):326-35. doi: 10.1002/mrd.20738.
6
Dynamics of a human seminal vesicle specific protein.一种人精囊特异性蛋白的动力学
Andrologia. 1990;22 Suppl 1:142-54.
7
Semenogelin I: a coagulum forming, multifunctional seminal vesicle protein.精液凝胶蛋白I:一种形成凝块的多功能精囊蛋白。
Cell Mol Life Sci. 1999 Jun;55(6-7):944-60. doi: 10.1007/s000180050346.
8
Cell biology of semenogelin.精液凝胶蛋白的细胞生物学
Andrologia. 1990;22 Suppl 1:132-41. doi: 10.1111/j.1439-0272.1990.tb02079.x.
9
[Advances in the study of Semenogelin I from human seminal vesicles].[人精囊分泌的凝固蛋白I的研究进展]
Zhonghua Nan Ke Xue. 2009 Apr;15(4):364-6.
10
Purification and characterization of the active precursor of a human sperm motility inhibitor secreted by the seminal vesicles: identity with semenogelin.精囊分泌的人精子运动抑制剂活性前体的纯化与特性鉴定:与精液凝胶蛋白的一致性
Biol Reprod. 1996 Oct;55(4):813-21. doi: 10.1095/biolreprod55.4.813.

引用本文的文献

1
Blocking serine protease activity prevents semenogelin degradation leading to hyperviscous semen in humans.阻断丝氨酸蛋白酶活性可防止精液凝固蛋白降解,导致人类精液呈现高粘性。
Biol Reprod. 2022 May 17;106(5):879-887. doi: 10.1093/biolre/ioac023.
2
Mechanism of semen liquefaction and its potential for a novel non-hormonal contraception†.精液液化的机制及其作为新型非激素避孕方法的潜力†。
Biol Reprod. 2020 Aug 4;103(2):411-426. doi: 10.1093/biolre/ioaa075.
3
Serine protease inhibitor disrupts sperm motility leading to reduced fertility in female mice†.
丝氨酸蛋白酶抑制剂破坏精子运动能力,导致雌性小鼠生育力降低†。
Biol Reprod. 2020 Aug 4;103(2):400-410. doi: 10.1093/biolre/ioaa049.
4
MicroRNAs in prostate cancer: From function to biomarker discovery.前列腺癌中的 microRNAs:从功能到生物标志物发现。
Exp Biol Med (Maywood). 2018 Jun;243(10):817-825. doi: 10.1177/1535370218775657.
5
Crucial role of estrogen for the mammalian female in regulating semen coagulation and liquefaction in vivo.雌激素对哺乳动物雌性在体内调节精液凝固和液化方面起着关键作用。
PLoS Genet. 2017 Apr 17;13(4):e1006743. doi: 10.1371/journal.pgen.1006743. eCollection 2017 Apr.
6
HIV-1 enhancing effect of prostatic acid phosphatase peptides is reduced in human seminal plasma.前列腺酸性磷酸酶肽对 HIV-1 的增强作用在人精液中降低。
PLoS One. 2011 Jan 20;6(1):e16285. doi: 10.1371/journal.pone.0016285.
7
Discovery and validation of urinary biomarkers for prostate cancer.前列腺癌尿液生物标志物的发现与验证
Proteomics Clin Appl. 2008 Mar 7;2(4):556-570. doi: 10.1002/prca.200780082.
8
Adapting mass spectrometry-based platforms for clinical proteomics applications: The capillary electrophoresis coupled mass spectrometry paradigm.使基于质谱的平台适用于临床蛋白质组学应用:毛细管电泳联用质谱范例。
Crit Rev Clin Lab Sci. 2009;46(3):129-52. doi: 10.1080/10408360902805261.
9
Twenty Years of PSA: From Prostate Antigen to Tumor Marker.前列腺特异性抗原的二十年:从前列腺抗原到肿瘤标志物
Rev Urol. 2007 Summer;9(3):113-23.
10
GPI-anchored complement regulatory proteins in seminal plasma. An analysis of their physical condition and the mechanisms of their binding to exogenous cells.精浆中的糖基磷脂酰肌醇锚定补体调节蛋白。其物理状态及与外源细胞结合机制的分析
J Clin Invest. 1996 Apr 1;97(7):1675-86. doi: 10.1172/JCI118594.