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小儿颌骨牙源性肿瘤——病例报告

Pediatric odontogenic tumor of the jaw - a case report.

作者信息

Muddana Keerthi, Pasupula Ajay Prakash, Dorankula Shyam Prasad Reddy, Thokala Madhusudan Rao, Muppallai Jaya Nagendra Krishna

机构信息

Senior Lecturer, Department of Oral and Maxillo Facial Pathology, Kamineni Institute of Dental Sciences , Narketpally, Nalgonda (dt), Andhra Pradesh, India .

Professor and HOD, Department of Oral and MaxilloFacial Pathology, Kamineni Institute of Dental Sciences , Narketpally, Nalgonda (dt), Andhra Pradesh, India .

出版信息

J Clin Diagn Res. 2014 Feb;8(2):250-2. doi: 10.7860/JCDR/2014/7650.4073. Epub 2014 Feb 3.

Abstract

Central jaw tumors (intra osseous) in children occur infrequently and few oral pathologists have had the opportunity or experience in diagnosing these lesions and predicting their biological behavior. Some children are not diagnosed correctly at the initial stages as having a neoplasm and are wrongly treated for infections by antibiotic administration. Subsequent to an unresponsive antibiotic therapy radiographs are taken to reveal a radiolucent or radio dense lesion in the jaws. Finally a tissue diagnosis becomes necessary in order to diagnose and initiate proper therapy. One among the central jaw tumors that occur infrequently in children is Ameloblastoma. It is often aggressive and destructive, with the capacity to attain great size, erode bone and invade adjacent structures. Ameloblastoma not only accounts for 1% of all tumors of maxilla and mandible but also 11% of all odontogenic tumors. It has a high percentage of local recurrence rate and possible malignant development when treated inadequately. Here we present a central jaw tumor in an 8-year-old child which was a case of unusually large plexiform ameloblastoma involving entire ramus up to the condyle, and part of body of the mandible.

摘要

儿童颌骨中心性肿瘤(骨内肿瘤)很少见,很少有口腔病理学家有机会或经验来诊断这些病变并预测其生物学行为。一些儿童在初始阶段未被正确诊断为患有肿瘤,而是被错误地当作感染使用抗生素治疗。在抗生素治疗无效后,会进行X光检查以发现颌骨中的透射或致密病变。最后,为了进行诊断并开始适当的治疗,组织诊断变得必要。儿童中很少见的颌骨中心性肿瘤之一是成釉细胞瘤。它通常具有侵袭性和破坏性,能够长得很大,侵蚀骨质并侵犯相邻结构。成釉细胞瘤不仅占上颌骨和下颌骨所有肿瘤的1%,还占所有牙源性肿瘤的11%。如果治疗不当,其局部复发率很高,并且可能发生恶性变。在此,我们报告一例8岁儿童的颌骨中心性肿瘤,该病例为罕见的巨大丛状成釉细胞瘤,累及整个下颌支直至髁突以及部分下颌体。

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本文引用的文献

1
Plexiform ameloblastoma.丛状成釉细胞瘤
Int J Clin Pediatr Dent. 2012 Jan;5(1):78-83. doi: 10.5005/jp-journals-10005-1140. Epub 2012 Feb 24.
2
Long-term follow up on recurrence of 305 ameloblastoma cases.305例成釉细胞瘤复发情况的长期随访
Int J Oral Maxillofac Surg. 2007 Apr;36(4):283-8. doi: 10.1016/j.ijom.2006.11.003. Epub 2007 Jan 11.
4
Recurrent ameloblastoma of the anterior skull base: three cases treated by radical resections.
J Craniomaxillofac Surg. 2006 Oct;34(7):412-4. doi: 10.1016/j.jcms.2006.06.001. Epub 2006 Oct 20.
8
Cell proliferation and chromosomal changes in human ameloblastoma.人成釉细胞瘤中的细胞增殖与染色体变化
Cancer Genet Cytogenet. 2002 Jul 1;136(1):31-7. doi: 10.1016/s0165-4608(02)00512-5.
9
Odontogenic tumors in Chile: a study of 362 cases.智利的牙源性肿瘤:一项对362例病例的研究。
J Oral Pathol Med. 2002 Aug;31(7):415-20. doi: 10.1034/j.1600-0714.2002.00073.x.

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