Tjepkema Jennifer, Bell Cynthia M, Soukup Jason W
Pacific Coast Veterinary Dentistry, Encinitas CA, USA.
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.
J Vet Dent. 2020 Mar;37(1):6-13. doi: 10.1177/0898756420924847. Epub 2020 May 26.
A noninductive tumor of odontogenic epithelium occurs within the tooth bearing regions of the jaw in dogs and fits the conventional definition of ameloblastoma, which is distinct from, and less common than, canine acanthomatous ameloblastoma. In order to clarify the clinical and radiological features of this uncommon odontogenic tumor in dogs, we performed a retrospective study of 20 dogs that were diagnosed between 2007 and 2015. Follow-up information was obtained for 17 of 20 dogs. The study group of dogs showed no apparent age, breed, or gender predilection. Conventional ameloblastoma is typically slow growing, well demarcated, and locally destructive. Tumors most commonly occurred as a mass or focal bony swelling within the maxilla (13/20) or mandible (7/20). Based on cases with available diagnostic imaging, as either dental radiographs or computed tomographic images, the tumors were usually intraosseous and caused mixed lytic/proliferative bone changes. Nevertheless, conventional ameloblastomas did not aggressively infiltrate adjacent tissues and recurrence was not observed within the study group, even in patients with narrow surgical margins or treatment by cyst enucleation.
一种非诱导性牙源性上皮肿瘤发生于犬颌骨的牙齿萌出区域，符合成釉细胞瘤的传统定义，与犬棘皮瘤性成釉细胞瘤不同，且较后者少见。为明确这种犬罕见牙源性肿瘤的临床和放射学特征，我们对2007年至2015年间诊断的20只犬进行了回顾性研究。20只犬中有17只获得了随访信息。该研究组犬未表现出明显的年龄、品种或性别偏好。传统成釉细胞瘤通常生长缓慢，边界清晰，具有局部破坏性。肿瘤最常见于上颌骨（13/20）或下颌骨（7/20）内的肿块或局限性骨肿胀。根据有诊断性影像学资料（牙科X线片或计算机断层扫描图像）的病例，肿瘤通常位于骨内，导致骨质呈溶骨/增殖性混合改变。然而，传统成釉细胞瘤不会侵袭性浸润相邻组织，即使手术切缘狭窄或采用囊肿摘除术治疗的研究组患者也未观察到复发。
